Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 99420..99964 Replicon chromosome
Accession NZ_CP096227
Organism Xanthomonas citri pv. citri strain CQ13

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag XCQ_RS00430 Protein ID WP_015462700.1
Coordinates 99686..99964 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID H8FI25
Locus tag XCQ_RS00425 Protein ID WP_003487884.1
Coordinates 99420..99677 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XCQ_RS00410 (XCQ_00410) 94539..96020 - 1482 WP_015462698.1 ribonuclease H-like domain-containing protein -
XCQ_RS00415 (XCQ_00415) 96017..98512 - 2496 WP_015462699.1 DEAD/DEAH box helicase -
XCQ_RS00420 (XCQ_00420) 98690..99352 + 663 WP_005912558.1 hemolysin III family protein -
XCQ_RS00425 (XCQ_00425) 99420..99677 + 258 WP_003487884.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
XCQ_RS00430 (XCQ_00430) 99686..99964 + 279 WP_015462700.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XCQ_RS00440 (XCQ_00440) 100144..101043 - 900 WP_011050073.1 SDR family NAD(P)-dependent oxidoreductase -
XCQ_RS00445 (XCQ_00445) 101103..101840 - 738 WP_003487890.1 SDR family oxidoreductase -
XCQ_RS00450 (XCQ_00450) 101966..102877 + 912 WP_011050074.1 LysR family transcriptional regulator -
XCQ_RS00455 (XCQ_00455) 103043..104116 - 1074 WP_040107715.1 ATP-grasp fold amidoligase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10400.97 Da        Isoelectric Point: 10.1557

>T242886 WP_015462700.1 NZ_CP096227:99686-99964 [Xanthomonas citri pv. citri]
VPALADLDAIADYIAIDNAPAAAALVKRVFGHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRIVVVHVMR
SERALRGNRLSR

Download         Length: 279 bp

>T242886 NZ_OW967975:2713329-2713436 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9683.21 Da        Isoelectric Point: 9.8274

>AT242886 WP_003487884.1 NZ_CP096227:99420-99677 [Xanthomonas citri pv. citri]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQARHRM
ARWLK

Download         Length: 258 bp

>AT242886 NZ_OW967975:c2713282-2713216 [Escherichia coli]
TGTCTGGTTTCAAGATTAGCCCCCGTTTTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB H8FI25

References