Detailed information of TA system TA242861

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 3387627..3388333
• Replicon: chromosome
• Accession: NZ_CP096201
• Organism: Kluyvera ascorbata strain SK

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: MY052_RS16185
• Protein ID: WP_248537412.1
• Coordinates: 3387627..3388007 (+)
• Length: 127 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: MY052_RS16190
• Protein ID: WP_202216168.1
• Coordinates: 3388004..3388333 (+)
• Length: 110 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-2 (1-124)

Antitoxin

• Cro/C1-type helix-turn-helix domain (53-94)

Sequences

Toxin

Protein

• Length: 127 a.a.
• Molecular weight: 14118.30 Da
• Isoelectric Point: 10.0042

>T242861 WP_248537412.1 NZ_CP096201:3387627-3388007 [Kluyvera ascorbata]
MTIYKAKRFNQNTKKLGITDDVLLKAAEDIKQGVWEANLGGGVIKKRLPLQQGKSGGARTVIFFKYDRHIFFYDGWAKNS
VSSGNGKEIEDDELIAYRKLASAFLAFTDKDIAKLLITGFLVEVDK

Nucleotide

• Length: 381 bp

>T242861 NZ_OW967966:3053641-3054135 [Escherichia coli]
ATGATTCAGGCCCCCGAGCCACTCATGGCAAGGCATCAATTCACCTCTTTTTGCTCGGGAGTAGAAACGATGGATAACTG
GCTAAAGCAGAGAGCCCTAAAAAATCAGCTTGCCGGCGCATCACGTACATTTGTTAGCTGTGATACGTATAGCAACGTTT
TGGCATATTATTCGCTTGCTTCCAGCGCCGTTGAAACGTATGTCGCGACAGGACGATTTCGCCGAAATATGCCAGAACCG
ATCCCTGTTGTAGTACTTGGTCGTCTGGCAATAGATAAATCATTACAGGGTCAGGGCATCGGTCGTGCGATGGTCAGAGA
TGCCGGTCTACGAGTACTACAGGCGGCTGAAGTCATTGGTATTCGCGGAATGTTGGTCCATGCGTTATCAGACCAGGCCC
GTGAGTTTTATCTGCGAGTGGGGTTTGAACCATCGCCTGTCGATTCTATGATACTGATGGCAACATTGGCTGATTTGCAG
GAATGTCTTAAATAG

Antitoxin

Protein

• Length: 110 a.a.
• Molecular weight: 12034.19 Da
• Isoelectric Point: 10.5858

>AT242861 WP_202216168.1 NZ_CP096201:3388004-3388333 [Kluyvera ascorbata]
MTNKLKTILDDAKELNALGLMPENDVAEINKLLKARELKTRIAAVKMMSGEEIKAVRARFGMSQSILAHTLGMSKESVSK
WERNEIKPSGPALRILNTLAAKGPEVFTK

Nucleotide

• Length: 330 bp

>AT242861 NZ_OW967966:3053351-3053644 [Escherichia coli]
ATGGCAGCAGCCAATAACATTCCAGCCAGGCGCGAATCTTTAAACTTGCGCATAAAACCCGCAGAACGCGATCTTATAGA
CCGGGCCGCTAAAGCCCGAGGAAAAAATCGCTCCGAATTTGTCCTTGAGGCCGCCAGAGCCGCAGCTGAAGAGGCGCTCA
TTGAGCAGAGAATTTTCAGGATCGATTCTGATGATTACCAGCTATTTTTGAATCGTCTGGATCAGCCCCCCGCGCCCAAT
GCTGCATTACGCAAAACCATGCAAACACCCGCGCCGTGGGAGCAAAAAAAATGA