Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 2976496..2977327 Replicon chromosome
Accession NZ_CP096169
Organism Shewanella sp. JNE2

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag MZ182_RS13280 Protein ID WP_088585313.1
Coordinates 2976911..2977327 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag MZ182_RS13275 Protein ID WP_088585314.1
Coordinates 2976496..2976918 (+) Length 141 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MZ182_RS13250 (MZ182_13250) 2972819..2973103 - 285 WP_126491562.1 type II toxin-antitoxin system RelE/ParE family toxin -
MZ182_RS13255 (MZ182_13255) 2973093..2973332 - 240 WP_126491561.1 CopG family ribbon-helix-helix protein -
MZ182_RS13260 (MZ182_13260) 2974048..2975256 - 1209 WP_248067189.1 J domain-containing protein -
MZ182_RS13265 (MZ182_13265) 2975468..2975815 - 348 WP_126491559.1 type II toxin-antitoxin system RelE/ParE family toxin -
MZ182_RS13270 (MZ182_13270) 2975817..2976077 - 261 WP_115017884.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
MZ182_RS13275 (MZ182_13275) 2976496..2976918 + 423 WP_088585314.1 nucleotidyltransferase domain-containing protein Antitoxin
MZ182_RS13280 (MZ182_13280) 2976911..2977327 + 417 WP_088585313.1 DUF86 domain-containing protein Toxin
MZ182_RS13285 (MZ182_13285) 2977723..2979075 - 1353 WP_248067194.1 phosphoglucosamine mutase -
MZ182_RS13290 (MZ182_13290) 2979151..2981091 - 1941 WP_248067199.1 nucleoside-diphosphate sugar epimerase/dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(12-130)

Antitoxin

Polymerase beta, nucleotidyltransferase

(9-96)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16056.55 Da        Isoelectric Point: 7.3244

>T242816 WP_088585313.1 NZ_CP096169:2976911-2977327 [Shewanella sp. JNE2]
MNDIIINKIATIKRCIKRIQQVYGDGSMFKQDFTLQDSVILNLQRCCEASIDIANHINRQQQLGIPQSSRDSFTLLSQNK
IINQQLADNLKKMVGLRNIAVHDYQELNLDIVVHVVQHHLEDFEQFIEVIKFCPRMSY

Download         Length: 417 bp

>T242816 NZ_OW967795:c4201416-4201243 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTTCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 141 a.a.        Molecular weight: 15861.89 Da        Isoelectric Point: 5.1231

>AT242816 WP_088585314.1 NZ_CP096169:2976496-2976918 [Shewanella sp. JNE2]
MQQLNESIIINLLQDNIPQLRLIYLFGSYAQGTQHRNSDIDIAVLADVTLDNIARWQLAQKLASALDTDVDLVDLRTAST
VLCQQVVTQGKRLWGTRQDDEIFAVKTISMYQHLQAERQAIIDDATAKTTANDHRGRHFE

Download         Length: 423 bp

>AT242816 NZ_OW967795:c4201740-4201444 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCCGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAACTGAATGAAAACT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTCAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAGCATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References