Detailed information of TA system TA242809

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /DUF1778(antitoxin)
• Location: 4481103..4481575
• Replicon: chromosome
• Accession: NZ_CP096166
• Organism: Shewanella sp. JNE7

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: MZ097_RS19865
• Protein ID: WP_248138581.1
• Coordinates: 4481103..4481309 (-)
• Length: 69 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: A0A6N3J9J2
• Locus tag: MZ097_RS19870
• Protein ID: WP_011791159.1
• Coordinates: 4481306..4481575 (-)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MZ097_RS19840 (MZ097_19845)	4476482..4477255	+	774	WP_011918337.1	hypothetical protein	-
MZ097_RS19845 (MZ097_19850)	4477530..4478000	+	471	WP_248066743.1	hypothetical protein	-
MZ097_RS19850 (MZ097_19855)	4478120..4478812	+	693	WP_248066744.1	hypothetical protein	-
MZ097_RS19855 (MZ097_19860)	4479113..4479505	-	393	Protein_3853	GNAT family N-acetyltransferase	-
MZ097_RS19860 (MZ097_19865)	4479570..4481131	+	1562	WP_248085119.1	IS3 family transposase	-
MZ097_RS19865 (MZ097_19870)	4481103..4481309	-	207	WP_248138581.1	hypothetical protein	Toxin
MZ097_RS19870 (MZ097_19875)	4481306..4481575	-	270	WP_011791159.1	DUF1778 domain-containing protein	Antitoxin
MZ097_RS19875 (MZ097_19880)	4481778..4482344	-	567	WP_181811409.1	SEC-C metal-binding domain-containing protein	-
MZ097_RS19880 (MZ097_19885)	4482879..4483262	-	384	WP_248066747.1	GIY-YIG nuclease family protein	-
MZ097_RS19885 (MZ097_19890)	4483273..4485408	-	2136	WP_248066748.1	S9 family peptidase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Vibrio phage ICP1, Orf50 (5-81)

Sequences

Toxin

Protein

• Length: 69 a.a.
• Molecular weight: 7827.08 Da
• Isoelectric Point: 9.1227

>T242809 WP_248138581.1 NZ_CP096166:c4481309-4481103 [Shewanella sp. JNE7]
VSYSKIFKELDKSLHDRASFDCGEAELNDFIQTQAAKHMQAGISRTMAAFFKLVVTIDRFKRPFFPLL

Nucleotide

• Length: 207 bp

>T242809 NZ_OW967795:2357066-2357344 [Escherichia coli]
ATGATAATGAATTTCAGACACAAGGGATTGCGTGACTTGTTTCTTCTCGGCAAAACCTCCGGCGTTATACCGACGCAAGT
CAAACGATTACGCCACCGACTCGCTGTGATTGATGCAGCATGCTGTCTTGCTGATATCGATATGCCCGGTTACCGACTAC
ATCCGTTAAGCGGCGATCGCGATGGAATTTGGGCGATATCTGTCTCGGGCAACTGGCGAATCACATTTGAATTCGTCAAT
GGCGATGCATACATACTGGATTACGAGGACTATCACTGA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 9859.32 Da
• Isoelectric Point: 4.7037

>AT242809 WP_011791159.1 NZ_CP096166:c4481575-4481306 [Shewanella sp. JNE7]
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDATQVIAEHESVTVKADVFDQFIMACDEAKVPNKALREAA
AFTKNGEFK

Nucleotide

• Length: 270 bp

>AT242809 NZ_OW967795:2357344-2357628 [Escherichia coli]
ATGAAAATGGCCAATCATCCCCGCCCGGGGGACATTATTCAGGAATCACTGGACGAACTTAATGTCAGCCTGCGCGAGTT
TGCCAGAGCAATGGAAATTGCGCCCTCAACGGCAAGCCGATTGCTGACCGGAAAAGCAGCTTTGACGCCAGAAATGGCAA
TTAAACTTTCCGTGGTGATCGGCAGTTCGCCGCAAATGTGGCTGAATCTGCAAAATGCCTGGAGTCTGGCAGAGGCAGAA
AAAACAGTGGATGTGTCGCGACTGCGCCGTCTGGTTACGCAATAA

Structures

Antitoxin

• AlphaFold DB: A0A6N3J9J2