Detailed information of TA system TA242802

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ygfYX/Cpta(toxin)
• Location: 1210136..1210805
• Replicon: chromosome
• Accession: NZ_CP096166
• Organism: Shewanella sp. JNE7

Toxin (Protein)

• Gene name: ygfX
• Uniprot ID: -
• Locus tag: MZ097_RS05505
• Protein ID: WP_248084321.1
• Coordinates: 1210365..1210805 (+)
• Length: 147 a.a.

Antitoxin (Protein)

• Gene name: ygfY
• Uniprot ID: -
• Locus tag: MZ097_RS05500
• Protein ID: WP_014610118.1
• Coordinates: 1210136..1210384 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MZ097_RS05475 (MZ097_05475)	1205759..1206565	+	807	WP_248084323.1	prolipoprotein diacylglyceryl transferase	-
MZ097_RS05480 (MZ097_05480)	1206565..1207359	+	795	WP_011790287.1	thymidylate synthase	-
MZ097_RS05485 (MZ097_05485)	1207476..1208645	+	1170	WP_248084322.1	Na+/H+ antiporter NhaA	-
MZ097_RS05490 (MZ097_05490)	1208648..1209034	+	387	WP_011790285.1	hypothetical protein	-
MZ097_RS05495 (MZ097_05495)	1209142..1210050	+	909	WP_011790284.1	transcriptional activator NhaR	-
MZ097_RS05500 (MZ097_05500)	1210136..1210384	+	249	WP_014610118.1	succinate dehydrogenase assembly factor 2	Antitoxin
MZ097_RS05505 (MZ097_05505)	1210365..1210805	+	441	WP_248084321.1	hypothetical protein	Toxin
MZ097_RS05510 (MZ097_05510)	1210842..1212455	-	1614	WP_248065600.1	L-aspartate oxidase	-
MZ097_RS05515 (MZ097_05515)	1212645..1213223	+	579	WP_011790280.1	RNA polymerase sigma factor RpoE	-
MZ097_RS05520 (MZ097_05520)	1213250..1213870	+	621	WP_248065601.1	anti sigma-E factor RseA C-terminal domain-containing protein	-
MZ097_RS05525 (MZ097_05525)	1213883..1214815	+	933	WP_011790278.1	MucB/RseB C-terminal domain-containing protein	-
MZ097_RS05530 (MZ097_05530)	1214826..1215299	+	474	WP_011918888.1	SoxR reducing system RseC family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (6-135)

Antitoxin

• Flavinator of succinate dehydrogenase (7-78)

Sequences

Toxin

Protein

• Length: 147 a.a.
• Molecular weight: 17357.53 Da
• Isoelectric Point: 8.8774

>T242802 WP_248084321.1 NZ_CP096166:1210365-1210805 [Shewanella sp. JNE7]
VEEQHHSFSVKASFDQRLSLVVFMCVCSSSFLIWPYTEHWLVTLLRLGLFLLSVSFLIWQLWRLKDWRLSFMLNGKGDGR
LSTGEHFRILRRTWVTPFVCMIYIDVEENTRLVLLWADMFTGVDYRHLCRLLLKAKMLQAKSQVEI

Nucleotide

• Length: 441 bp

>T242802 NZ_OW967795:884271-884678 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATTCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGAAAACGGCA
ACATTTATGGCTGGCAGCTGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATATTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9545.15 Da
• Isoelectric Point: 4.5994

>AT242802 WP_014610118.1 NZ_CP096166:1210136-1210384 [Shewanella sp. JNE7]
MELMNIARVRWACRRGMLELDVLFQPFVENIYQDLSDIDKASFIRLLECEDPELFAWFMGHEACPDAELARMVVKVRGRA
AP

Nucleotide

• Length: 249 bp

>AT242802 NZ_OW967795:884024-884290 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA