Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 4252308..4253139 Replicon chromosome
Accession NZ_CP096163
Organism Shewanella sp. JNE10-2

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag MZ018_RS18785 Protein ID WP_088585313.1
Coordinates 4252723..4253139 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag MZ018_RS18780 Protein ID WP_088585314.1
Coordinates 4252308..4252730 (+) Length 141 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MZ018_RS18755 (MZ018_18755) 4248532..4248816 - 285 WP_126491562.1 type II toxin-antitoxin system RelE/ParE family toxin -
MZ018_RS18760 (MZ018_18760) 4248806..4249045 - 240 WP_126491561.1 CopG family ribbon-helix-helix protein -
MZ018_RS18765 (MZ018_18765) 4249761..4250969 - 1209 WP_248084660.1 J domain-containing protein -
MZ018_RS18770 (MZ018_18770) 4251181..4251528 - 348 WP_126491559.1 type II toxin-antitoxin system RelE/ParE family toxin -
MZ018_RS18775 (MZ018_18775) 4251530..4251790 - 261 WP_115017884.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
MZ018_RS18780 (MZ018_18780) 4252308..4252730 + 423 WP_088585314.1 nucleotidyltransferase domain-containing protein Antitoxin
MZ018_RS18785 (MZ018_18785) 4252723..4253139 + 417 WP_088585313.1 DUF86 domain-containing protein Toxin
MZ018_RS18790 (MZ018_18790) 4253535..4254887 - 1353 WP_248084661.1 phosphoglucosamine mutase -
MZ018_RS18795 (MZ018_18795) 4254962..4256902 - 1941 WP_248084662.1 nucleoside-diphosphate sugar epimerase/dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(12-130)

Antitoxin

Polymerase beta, nucleotidyltransferase

(9-96)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16056.55 Da        Isoelectric Point: 7.3244

>T242798 WP_088585313.1 NZ_CP096163:4252723-4253139 [Shewanella sp. JNE10-2]
MNDIIINKIATIKRCIKRIQQVYGDGSMFKQDFTLQDSVILNLQRCCEASIDIANHINRQQQLGIPQSSRDSFTLLSQNK
IINQQLADNLKKMVGLRNIAVHDYQELNLDIVVHVVQHHLEDFEQFIEVIKFCPRMSY

Download         Length: 417 bp

>T242798 NZ_OW967795:182689-182796 [Escherichia coli]
ATGACGCTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 141 a.a.        Molecular weight: 15861.89 Da        Isoelectric Point: 5.1231

>AT242798 WP_088585314.1 NZ_CP096163:4252308-4252730 [Shewanella sp. JNE10-2]
MQQLNESIIINLLQDNIPQLRLIYLFGSYAQGTQHRNSDIDIAVLADVTLDNIARWQLAQKLASALDTDVDLVDLRTAST
VLCQQVVTQGKRLWGTRQDDEIFAVKTISMYQHLQAERQAIIDDATAKTTANDHRGRHFE

Download         Length: 423 bp

>AT242798 NZ_OW967795:c182632-182574 [Escherichia coli]
TCAAGATTAGCCCCCGTGATGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References