Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc(toxin)
Location 3239658..3240217 Replicon chromosome
Accession NZ_CP096163
Organism Shewanella sp. JNE10-2

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag MZ018_RS14275 Protein ID WP_172591132.1
Coordinates 3239828..3240217 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag MZ018_RS14270 Protein ID WP_172591131.1
Coordinates 3239658..3239828 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MZ018_RS14245 (MZ018_14245) 3235282..3235962 - 681 WP_248084399.1 hypothetical protein -
MZ018_RS14250 (MZ018_14250) 3236181..3236474 - 294 WP_248084400.1 hypothetical protein -
MZ018_RS14255 (MZ018_14255) 3236658..3236957 - 300 Protein_2773 transposase -
MZ018_RS14260 (MZ018_14260) 3237003..3237161 + 159 WP_248084401.1 hypothetical protein -
MZ018_RS14265 (MZ018_14265) 3237706..3239532 + 1827 WP_248065872.1 site-specific integrase -
MZ018_RS14270 (MZ018_14270) 3239658..3239828 + 171 WP_172591131.1 acetyltransferase Antitoxin
MZ018_RS14275 (MZ018_14275) 3239828..3240217 + 390 WP_172591132.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
MZ018_RS14280 (MZ018_14280) 3240342..3243068 - 2727 WP_248065871.1 phage/plasmid primase, P4 family -
MZ018_RS14285 (MZ018_14285) 3243215..3243538 - 324 WP_248084402.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(1-125)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14212.28 Da        Isoelectric Point: 3.9777

>T242795 WP_172591132.1 NZ_CP096163:3239828-3240217 [Shewanella sp. JNE10-2]
MDIICFPFERVVEINALILSTEPGMKGAVDIPKLQGALSRIDNAIVYQGLDDVFEIAAKYTACIAVSHACPDANKRTGLA
VALEYLSLNDYEITEDNELLANAIRDLVLQEITETDFADILYAQYLKGL

Download         Length: 390 bp

>T242795 NZ_OW967518:c4808987-4808730 [Klebsiella oxytoca]
ATGAATCTATCCCGTCAGGAACAACGTACCTTACACGTTCTCGCTAAAGGTGGCCGGATCGCGCATATTCGCGATGCATC
AGGCCGCGTAACCTCTGTTGAATGCTACAGCCGCGAAGGGCTCCTGCTCAGCGACTGCACGCTCGCCGTTTTCAAAAAAC
TCAAAACCAAAAAACTCATTAAGTCCGTCAACGGGCAGCCCTACCGTATCAATACCACCGGACTGAACAACGTTCGCGCT
CAGCTGGACAACCGCTAA

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6414.58 Da        Isoelectric Point: 11.0174

>AT242795 WP_172591131.1 NZ_CP096163:3239658-3239828 [Shewanella sp. JNE10-2]
MNRKLEVYGVQVVTRPKIKATKQLDLSGDFGRQIVKSETKLALRTHPKTFQKLADM

Download         Length: 171 bp

>AT242795 NZ_OW967518:c4808719-4808168 [Klebsiella oxytoca]
ATGACAAACCATAACTTCACCTTTCACATCACCTCAGAGCGTGATGCTGATGATATTCGCGAAGTTGAAACCCGGGCCTT
CGGCTTTAGCAAAGAGGCCGATCTGGTTGCCGCTTTGCTCAACGATGAAAGTGCTCACCCGAGCTTATCTCTGCTGGCCA
AACATAATGGAAAAGCAGTTGGGCATATTTTGTTCACCCTGGCGACGTTCAAAGGGGAGTCTGACTCTCCGATGATGCAT
ATCCTTGCCCCCCTGGCGGTGGTGCCGGAATACCAGGGCGTGGGCGTAGGCGGATTGCTTATCCAGCGCGGTATTGAGCA
TCTGAAAGCCGCAGGAAGCGAGGCGGTATTTGTTCTGGGACATGCCGCTTATTACCCGCGGCATGGCTTTGAACCCTGTG
CCGGAGATAAAGGCTATCCGGCGCCTTATCCCATTCCCGAGGAGCATAAAGCCTGCTGGATGCTGCAGCGGCTTTCGTCC
CGGCCGCTGGGGAGAACCGGTCAGATACAGTGCGCCCGGGCGTTAATGAAACCCGAGCACTGGCGCGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References