Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ParE-CopA/ParE-RHH
Location 3200215..3200780 Replicon chromosome
Accession NZ_CP096163
Organism Shewanella sp. JNE10-2

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag MZ018_RS14090 Protein ID WP_248084373.1
Coordinates 3200215..3200508 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name copA Uniprot ID -
Locus tag MZ018_RS14095 Protein ID WP_115014944.1
Coordinates 3200496..3200780 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MZ018_RS14065 (MZ018_14065) 3195304..3195732 + 429 WP_248084371.1 DUF86 domain-containing protein -
MZ018_RS14070 (MZ018_14070) 3196165..3197241 + 1077 WP_076500105.1 hypothetical protein -
MZ018_RS14075 (MZ018_14075) 3197386..3197598 + 213 WP_076500103.1 AlpA family phage regulatory protein -
MZ018_RS21750 3197656..3198114 + 459 WP_262918164.1 YfjI family protein -
MZ018_RS14080 (MZ018_14080) 3198140..3199192 + 1053 Protein_2738 YfjI family protein -
MZ018_RS14085 (MZ018_14085) 3199395..3200072 + 678 WP_264302493.1 inovirus Gp2 family protein -
MZ018_RS14090 (MZ018_14090) 3200215..3200508 - 294 WP_248084373.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MZ018_RS14095 (MZ018_14095) 3200496..3200780 - 285 WP_115014944.1 CopG family ribbon-helix-helix protein Antitoxin
MZ018_RS14100 (MZ018_14100) 3201065..3201787 - 723 WP_248084374.1 lecithin retinol acyltransferase family protein -
MZ018_RS14105 (MZ018_14105) 3201868..3202434 - 567 WP_028760122.1 site-specific integrase -
MZ018_RS14110 (MZ018_14110) 3202543..3202950 - 408 WP_248084375.1 DUF2787 domain-containing protein -
MZ018_RS14115 (MZ018_14115) 3203087..3203206 - 120 Protein_2745 site-specific integrase -
MZ018_RS14120 (MZ018_14120) 3203394..3203492 + 99 WP_248084376.1 AlpA family phage regulatory protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-44)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11139.68 Da        Isoelectric Point: 5.8404

>T242794 WP_248084373.1 NZ_CP096163:c3200508-3200215 [Shewanella sp. JNE10-2]
MPQIIFTATAVRDLERLREFLRTKNPPAAQRAASAIINTIRKLESYPDIGRPIDDNDFSFRELLIDFGDTGYLAMYQYDG
GERLTVLCIRHQKEAGY

Download         Length: 294 bp

>T242794 NZ_OW967518:4545068-4545286 [Klebsiella oxytoca]
ATGTCTGATAAAACATTAACCAAAATAGACTATTTGATGCGCTTACGACGTTGTCAGACAATTGATACGCTGGAGCGCGT
AATTGAAAAAAATAAATATGAACTTTCTGATAATGAACTGGCGGTATTTTACTCAGCAGCCGATCATCGTCTTGCTGAAC
TGACGATGAATAAACTGTATGACAAGATCCCGCCATCGGTCTGGAAATTCATCCGCTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10941.26 Da        Isoelectric Point: 6.3342

>AT242794 WP_115014944.1 NZ_CP096163:c3200780-3200496 [Shewanella sp. JNE10-2]
MSTIKPVSVKLDADIKARVEHLAETRKRSSHWMMREAIREYVEREEKREALQQEALRAWEEHQTSGLHVTGDEVVSWLES
WGSENEKAAPSCHK

Download         Length: 285 bp

>AT242794 NZ_OW967518:4544667-4545041 [Klebsiella oxytoca]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCGCAGCTTAAATTTCTCTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTTAATGACCCAACCTCTGCTGTCAATCTTCAGCTTAATGAATTGATCGAGC
ACATTGCCGCGTTCGCACTTAATTATAAAATTAAGTATGCTGAGGATAATAAGCTGGTGACTCAGCTTGACGAATATCTG
GATGACACTTTCGTGTTGTTCAGCAACTACGGCATTAACACTGCAGATCTGCAGAAATGGCGTAAATCAGGCAACAGGTT
ATTCCGCTGCTTTGTGAACGCCAGTCGGGAAAACCCGGCCAGTCTTTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References