242793

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 2399665..2400334 Replicon chromosome
Accession NZ_CP096163
Organism Shewanella sp. JNE10-2

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag MZ018_RS10565 Protein ID WP_248084321.1
Coordinates 2399894..2400334 (+) Length 147 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag MZ018_RS10560 Protein ID WP_014610118.1
Coordinates 2399665..2399913 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MZ018_RS10535 (MZ018_10535) 2395288..2396094 + 807 WP_248084323.1 prolipoprotein diacylglyceryl transferase -
MZ018_RS10540 (MZ018_10540) 2396094..2396888 + 795 WP_011790287.1 thymidylate synthase -
MZ018_RS10545 (MZ018_10545) 2397005..2398174 + 1170 WP_248084322.1 Na+/H+ antiporter NhaA -
MZ018_RS10550 (MZ018_10550) 2398177..2398563 + 387 WP_011790285.1 hypothetical protein -
MZ018_RS10555 (MZ018_10555) 2398671..2399579 + 909 WP_011790284.1 transcriptional activator NhaR -
MZ018_RS10560 (MZ018_10560) 2399665..2399913 + 249 WP_014610118.1 succinate dehydrogenase assembly factor 2 Antitoxin
MZ018_RS10565 (MZ018_10565) 2399894..2400334 + 441 WP_248084321.1 hypothetical protein Toxin
MZ018_RS10570 (MZ018_10570) 2400371..2401984 - 1614 WP_248065600.1 L-aspartate oxidase -
MZ018_RS10575 (MZ018_10575) 2402174..2402752 + 579 WP_011790280.1 RNA polymerase sigma factor RpoE -
MZ018_RS10580 (MZ018_10580) 2402779..2403399 + 621 WP_248065601.1 anti sigma-E factor RseA C-terminal domain-containing protein -
MZ018_RS10585 (MZ018_10585) 2403412..2404344 + 933 WP_011790278.1 MucB/RseB C-terminal domain-containing protein -
MZ018_RS10590 (MZ018_10590) 2404355..2404828 + 474 WP_011918888.1 SoxR reducing system RseC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(6-135)

Antitoxin

Flavinator of succinate dehydrogenase

(7-78)


Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 17357.53 Da        Isoelectric Point: 8.8774

>T242793 WP_248084321.1 NZ_CP096163:2399894-2400334 [Shewanella sp. JNE10-2]
VEEQHHSFSVKASFDQRLSLVVFMCVCSSSFLIWPYTEHWLVTLLRLGLFLLSVSFLIWQLWRLKDWRLSFMLNGKGDGR
LSTGEHFRILRRTWVTPFVCMIYIDVEENTRLVLLWADMFTGVDYRHLCRLLLKAKMLQAKSQVEI

Download         Length: 441 bp

>T242793 NZ_OW967518:2197117-2197220 [Klebsiella oxytoca]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTTTTTTT

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9545.15 Da        Isoelectric Point: 4.5994

>AT242793 WP_014610118.1 NZ_CP096163:2399665-2399913 [Shewanella sp. JNE10-2]
MELMNIARVRWACRRGMLELDVLFQPFVENIYQDLSDIDKASFIRLLECEDPELFAWFMGHEACPDAELARMVVKVRGRA
AP

Download         Length: 249 bp

>AT242793 NZ_OW967518:c2197224-2197082 [Klebsiella oxytoca]
AGATAAAAAAAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References