Detailed information of TA system TA242791

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /DUF1778(antitoxin)
• Location: 998211..998683
• Replicon: chromosome
• Accession: NZ_CP096163
• Organism: Shewanella sp. JNE10-2

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: MZ018_RS04205
• Protein ID: WP_248138581.1
• Coordinates: 998211..998417 (-)
• Length: 69 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: A0A6N3J9J2
• Locus tag: MZ018_RS04210
• Protein ID: WP_011791159.1
• Coordinates: 998414..998683 (-)
• Length: 90 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MZ018_RS04180 (MZ018_04180)	993590..994363	+	774	WP_011918337.1	hypothetical protein	-
MZ018_RS04185 (MZ018_04185)	994638..995108	+	471	WP_248066743.1	hypothetical protein	-
MZ018_RS04190 (MZ018_04190)	995228..995920	+	693	WP_248066744.1	hypothetical protein	-
MZ018_RS04195 (MZ018_04195)	996221..996613	-	393	Protein_817	GNAT family N-acetyltransferase	-
MZ018_RS04200 (MZ018_04200)	996678..998239	+	1562	WP_248085119.1	IS3 family transposase	-
MZ018_RS04205 (MZ018_04205)	998211..998417	-	207	WP_248138581.1	hypothetical protein	Toxin
MZ018_RS04210 (MZ018_04210)	998414..998683	-	270	WP_011791159.1	DUF1778 domain-containing protein	Antitoxin
MZ018_RS04215 (MZ018_04215)	998886..999452	-	567	WP_181811409.1	SEC-C metal-binding domain-containing protein	-
MZ018_RS04220 (MZ018_04220)	999987..1000370	-	384	WP_248066747.1	GIY-YIG nuclease family protein	-
MZ018_RS04225 (MZ018_04225)	1000381..1002516	-	2136	WP_248066748.1	S9 family peptidase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Vibrio phage ICP1, Orf50 (5-81)

Sequences

Toxin

Protein

• Length: 69 a.a.
• Molecular weight: 7827.08 Da
• Isoelectric Point: 9.1227

>T242791 WP_248138581.1 NZ_CP096163:c998417-998211 [Shewanella sp. JNE10-2]
VSYSKIFKELDKSLHDRASFDCGEAELNDFIQTQAAKHMQAGISRTMAAFFKLVVTIDRFKRPFFPLL

Nucleotide

• Length: 207 bp

>T242791 NZ_OW967518:901865-902275 [Klebsiella oxytoca]
GTGGTCCTGTGGCAATCTGATTTACGCATCTCGTGGCGAGCGCAATGGTTCTCACTGTTGATGCACGGCGTGGTGGCGGC
GCTGGTGCTGGTGTTGCCCTGGCCGCTGAGCTATACCCCGCTGTGGCTGATACTGCTGTCGCTGGTGGTGTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGACAGGGGGAAATAAAGCTGCTGATTGACTCTCGCCTGCGCTGGCAAAAAGCG
GAGTGGGATATCGTCGGCACCCCGTGGGTAATCAATAGCGGAATGCTGCTGCGTCTGCGAAATACGGAAAACCAACGCAC
TCAGCATCTATGGGTGGCGGCGGATAGCATGGACGCGGGCGAGTGGCGCGATCTGCGTCGGCTGGTGTTACAGAAACCGA
CGCAAGATTAA

Antitoxin

Protein

• Length: 90 a.a.
• Molecular weight: 9859.32 Da
• Isoelectric Point: 4.7037

>AT242791 WP_011791159.1 NZ_CP096163:c998683-998414 [Shewanella sp. JNE10-2]
MATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDATQVIAEHESVTVKADVFDQFIMACDEAKVPNKALREAA
AFTKNGEFK

Nucleotide

• Length: 270 bp

>AT242791 NZ_OW967518:901618-901884 [Klebsiella oxytoca]
ATGGATATTAACAATAAAGCTCGCATCCACTGGGCATGCCGCCGGGGAATGCGTGAACTCGATATCTCCATCATGCCGTT
TTTTGAGCATGAGTACGATACGCTCAGTGATGACGATAAGCGGTTGTTCATCCGCCTGCTGGAAAATGACGATCCGGACC
TGTTCAACTGGTTGATGAACCATGGCGAACCGGCTGATGCAGAACTGCAGCGGATGGTAAAATTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Structures

Antitoxin

• AlphaFold DB: A0A6N3J9J2