242786

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 316791..317152 Replicon chromosome
Accession NZ_CP096141
Organism Xanthomonas prunicola strain CIX383

Toxin (Protein)


Gene name EcnB Uniprot ID A0A836P2V1
Locus tag M0D48_RS01280 Protein ID WP_010374872.1
Coordinates 317018..317152 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A836P2N2
Locus tag M0D48_RS01275 Protein ID WP_010374875.1
Coordinates 316791..316943 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0D48_RS01245 (M0D48_01240) 311880..312563 - 684 WP_252161740.1 dTMP kinase -
M0D48_RS01250 (M0D48_01245) 313010..313552 - 543 WP_252161741.1 GTPase -
M0D48_RS01255 (M0D48_01250) 313549..314466 - 918 WP_252161742.1 hypothetical protein -
M0D48_RS01260 (M0D48_01255) 314564..314923 - 360 WP_252161743.1 roadblock/LC7 domain-containing protein -
M0D48_RS01265 (M0D48_01260) 314987..315439 - 453 WP_252161744.1 roadblock/LC7 domain-containing protein -
M0D48_RS01270 (M0D48_01265) 315760..316683 + 924 WP_252161745.1 arginase -
M0D48_RS01275 (M0D48_01270) 316791..316943 + 153 WP_010374875.1 entericidin A/B family lipoprotein Antitoxin
M0D48_RS01280 (M0D48_01275) 317018..317152 + 135 WP_010374872.1 entericidin A/B family lipoprotein Toxin
M0D48_RS01285 (M0D48_01280) 317392..317601 + 210 WP_017117799.1 CsbD family protein -
M0D48_RS01290 (M0D48_01285) 317768..319057 + 1290 WP_252161746.1 tryptophan--tRNA ligase -
M0D48_RS01295 (M0D48_01290) 319128..320133 + 1006 Protein_248 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4475.37 Da        Isoelectric Point: 10.2040

>T242786 WP_010374872.1 NZ_CP096141:317018-317152 [Xanthomonas prunicola]
MKRAIVLLVLSMLSVGMLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T242786 NZ_OW967388:c1805655-1805476 [Enterobacter cloacae]
ATGGATAGCAGGAATGCAATAGCAATGATAGAAGCCGATGGGTGGTATCTGGTGAGAGTGAAAGGCAGCCATCACCAGTT
CAAACACCCAACGAAAAAGGGGCTGGTAACGGTAAAGCATCCACAGAAAGACATACCGTTACCAACACTGAAAAGCATCA
AAAAACAGGCGGGGCTCTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5065.02 Da        Isoelectric Point: 8.7942

>AT242786 WP_010374875.1 NZ_CP096141:316791-316943 [Xanthomonas prunicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT242786 NZ_OW967388:c1805454-1805044 [Enterobacter cloacae]
ATGTTGTACCCTGTTGCTATTGATAAAGGCGATTCATCCTTCGGCGTTCGCGTACCTGATATTCCTGGCTGCTTCTCTGG
CGGTGATGATTATCAGGACGCGATTGAAAGCGTACGTGAAGCGATCGAGGCACACATCGAATTACTGGTTGAAGATGGCG
AGAGCGTTCCAGAAGCAACGACCGTCGAAAACTGGCTTTCTGATCCGGAGTATGCCGGTGCTGTATGGGCCCTGGTTGAC
GTGGATATAACTCGTCTGATGGGAAAAGCGGAAAAAATCAATGTGACGCTTCCTTCACTGCTGATCCGACGTATCGATCA
GTTTGTGGCCGCGCATCCTGAATATGGCAGCCGGTCTGGCTTCCTGTCTCGTGTCGCGGCAGATAAAGTAATTGGACGAG
AAAAACGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A836P2V1

Antitoxin

Source ID Structure
AlphaFold DB A0A836P2N2

References