242785

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3071511..3071872 Replicon chromosome
Accession NZ_CP096140
Organism Xanthomonas prunicola strain MAI5037

Toxin (Protein)


Gene name EcnB Uniprot ID A0A836P2V1
Locus tag M0D47_RS12910 Protein ID WP_010374872.1
Coordinates 3071738..3071872 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A836P2N2
Locus tag M0D47_RS12905 Protein ID WP_010374875.1
Coordinates 3071511..3071663 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0D47_RS12875 (M0D47_12855) 3066600..3067283 - 684 WP_252161740.1 dTMP kinase -
M0D47_RS12880 (M0D47_12860) 3067730..3068272 - 543 WP_252161741.1 GTPase -
M0D47_RS12885 (M0D47_12865) 3068269..3069186 - 918 WP_252161742.1 hypothetical protein -
M0D47_RS12890 (M0D47_12870) 3069284..3069643 - 360 WP_252161743.1 roadblock/LC7 domain-containing protein -
M0D47_RS12895 (M0D47_12875) 3069707..3070159 - 453 WP_252161744.1 roadblock/LC7 domain-containing protein -
M0D47_RS12900 (M0D47_12880) 3070480..3071403 + 924 WP_252161745.1 arginase -
M0D47_RS12905 (M0D47_12885) 3071511..3071663 + 153 WP_010374875.1 entericidin A/B family lipoprotein Antitoxin
M0D47_RS12910 (M0D47_12890) 3071738..3071872 + 135 WP_010374872.1 entericidin A/B family lipoprotein Toxin
M0D47_RS12915 (M0D47_12895) 3072112..3072321 + 210 WP_017117799.1 CsbD family protein -
M0D47_RS12920 (M0D47_12900) 3072488..3073777 + 1290 WP_252161746.1 tryptophan--tRNA ligase -
M0D47_RS12925 (M0D47_12905) 3073848..3074853 + 1006 Protein_2512 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4475.37 Da        Isoelectric Point: 10.2040

>T242785 WP_010374872.1 NZ_CP096140:3071738-3071872 [Xanthomonas prunicola]
MKRAIVLLVLSMLSVGMLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T242785 NZ_OW967388:c1176307-1175996 [Enterobacter cloacae]
ATGCACATAGTCTCAAGAGCGCCTTTCGACACAGCGGCCAGACATTATCCCAATCAAGCACAAGCCCTGGACGATCTTTA
CCGGGTACTAAAAAAGGAACACTACCCCTCACCAGACGAGATGCGAAAGCGCTTTCCCAGCCTGGACCGGATGAAATACC
GGGAAAAATGGTGGGTCATTGATGTGGGTGGCGGGCATCTAAGAGTAATGTTTTTTGCTGATTTTGAGCGGGGAAAGTTC
TTCATCAAACACATCAGCACGCACGCAGAGTATGACAAGCTCACGGACTACTATCGGAGAACGAAAGAATGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5065.02 Da        Isoelectric Point: 8.7942

>AT242785 WP_010374875.1 NZ_CP096140:3071511-3071663 [Xanthomonas prunicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT242785 NZ_OW967388:c1175999-1175580 [Enterobacter cloacae]
ATGAATTATGCAGCAGCCATCAAAGCGGCAAACGCTCTGACAAACGAACTCCCTTTCCTGGGTTCAAGCCCGTCGCGGCA
AGACTACGAGGATGCGCTGGCGCTGGTGGAGTATCTTATCGAGCACGACCCGGATAACCCGCTGGTAGAGATGCTTACTG
CCAAAATCGATAAGTACGAAAACGAGTCCCCGGAGTTTGCAGAATTTAACGCGCGTATTGCCAGTATTCCGTCAGGCGTT
GCGTTACTGCGAACGCTAATGGATCAGTACCAGCTCACTCAGAGCGACTTCGAGAACGAGATTGGTAAGAAGTCTCTGGT
AAGTCGGATCCTGAACGGACAGCGCACGTTAACGCTGGATCATATGCGGGCGCTGGCGAAGCGTTTTGGTTTGCCGGTGA
GCGCATTTGTGGGGAATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A836P2V1

Antitoxin

Source ID Structure
AlphaFold DB A0A836P2N2

References