242784

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2172203..2172564 Replicon chromosome
Accession NZ_CP096139
Organism Xanthomonas prunicola strain MAI5069

Toxin (Protein)


Gene name EcnB Uniprot ID A0A836P2V1
Locus tag M0D45_RS09240 Protein ID WP_010374872.1
Coordinates 2172203..2172337 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A836P2N2
Locus tag M0D45_RS09245 Protein ID WP_010374875.1
Coordinates 2172412..2172564 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0D45_RS09225 (M0D45_09215) 2169222..2170227 - 1006 Protein_1791 MBL fold metallo-hydrolase -
M0D45_RS09230 (M0D45_09220) 2170298..2171587 - 1290 WP_260815389.1 tryptophan--tRNA ligase -
M0D45_RS09235 (M0D45_09225) 2171754..2171963 - 210 WP_017117799.1 CsbD family protein -
M0D45_RS09240 (M0D45_09230) 2172203..2172337 - 135 WP_010374872.1 entericidin A/B family lipoprotein Toxin
M0D45_RS09245 (M0D45_09235) 2172412..2172564 - 153 WP_010374875.1 entericidin A/B family lipoprotein Antitoxin
M0D45_RS09250 (M0D45_09240) 2172672..2173595 - 924 WP_260815388.1 arginase -
M0D45_RS09255 (M0D45_09245) 2173918..2174370 + 453 WP_252161744.1 roadblock/LC7 domain-containing protein -
M0D45_RS09260 (M0D45_09250) 2174434..2174793 + 360 WP_252161743.1 roadblock/LC7 domain-containing protein -
M0D45_RS09265 (M0D45_09255) 2174891..2175808 + 918 WP_260817977.1 hypothetical protein -
M0D45_RS09270 (M0D45_09260) 2175805..2176347 + 543 WP_252161741.1 GTPase -
M0D45_RS09275 (M0D45_09265) 2176794..2177477 + 684 WP_260817978.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4475.37 Da        Isoelectric Point: 10.2040

>T242784 WP_010374872.1 NZ_CP096139:c2172337-2172203 [Xanthomonas prunicola]
MKRAIVLLVLSMLSVGMLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T242784 NZ_OW967388:c1082038-1081820 [Enterobacter cloacae]
ATGTCTGATAAACCATTAACAAAAGTCGATTATTTGATGCGCCTGCGACGCTGCCAGTCAATTGACACCCTCGAACGTGT
TATTGAAAAAAATAAATACGAGCTCTCTGATAATGAACTGGCGGTATTTTATTCAGCTGCCGACCATCGTCTGGCTGAAC
TAACCATGAATAAACTGTATGACAAGATCCCCTCTTCGGTATGGAAATTTGTTCGTTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5065.02 Da        Isoelectric Point: 8.7942

>AT242784 WP_010374875.1 NZ_CP096139:c2172564-2172412 [Xanthomonas prunicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT242784 NZ_OW967388:c1082440-1082066 [Enterobacter cloacae]
ATGGACGAGTACTCGCCAAAAAGGCATGATATCGCGCAGTTGAAATTTCTCTGCGAATCCTTGTACCATGACTGCCTTGC
CAATCTTGAAGAAAGTAACCATGGCTGGGTGAACGATCCAACGTCTGCTATCAATTTACAGCTTAACGAGCTGATCGAGC
ATATCGCCACCTTCGCACTTAATTATAAAATTAAGTACAATGAAGATAATAAGTTGATAGAGCAAATTGATGAATACCTG
GACGACACCTTTATGTTGTTCAGCAGCTACGGCATTAACGCACAGGATTTGCAGAAATGGCGTAAATCAGGAAACCGCCT
ATTTCGCTGCTTCACTAATGTCAGCAGAGCTAATCCGGTTAGTCTTTCCTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A836P2V1

Antitoxin

Source ID Structure
AlphaFold DB A0A836P2N2

References