242783

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3069986..3070347 Replicon chromosome
Accession NZ_CP096138
Organism Xanthomonas prunicola strain MAI5084

Toxin (Protein)


Gene name EcnB Uniprot ID A0A836P2V1
Locus tag M0D44_RS12885 Protein ID WP_010374872.1
Coordinates 3070213..3070347 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A836P2N2
Locus tag M0D44_RS12880 Protein ID WP_010374875.1
Coordinates 3069986..3070138 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0D44_RS12850 (M0D44_12825) 3065075..3065758 - 684 WP_252161740.1 dTMP kinase -
M0D44_RS12855 (M0D44_12830) 3066205..3066747 - 543 WP_252161741.1 GTPase -
M0D44_RS12860 (M0D44_12835) 3066744..3067661 - 918 WP_252161742.1 hypothetical protein -
M0D44_RS12865 (M0D44_12840) 3067759..3068118 - 360 WP_252161743.1 roadblock/LC7 domain-containing protein -
M0D44_RS12870 (M0D44_12845) 3068182..3068634 - 453 WP_252161744.1 roadblock/LC7 domain-containing protein -
M0D44_RS12875 (M0D44_12850) 3068955..3069878 + 924 WP_252161745.1 arginase -
M0D44_RS12880 (M0D44_12855) 3069986..3070138 + 153 WP_010374875.1 entericidin A/B family lipoprotein Antitoxin
M0D44_RS12885 (M0D44_12860) 3070213..3070347 + 135 WP_010374872.1 entericidin A/B family lipoprotein Toxin
M0D44_RS12890 (M0D44_12865) 3070587..3070796 + 210 WP_017117799.1 CsbD family protein -
M0D44_RS12895 (M0D44_12870) 3070963..3072252 + 1290 WP_252161746.1 tryptophan--tRNA ligase -
M0D44_RS12900 (M0D44_12875) 3072323..3073328 + 1006 Protein_2507 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4475.37 Da        Isoelectric Point: 10.2040

>T242783 WP_010374872.1 NZ_CP096138:3070213-3070347 [Xanthomonas prunicola]
MKRAIVLLVLSMLSVGMLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T242783 NZ_OW967388:581754-582095 [Enterobacter cloacae]
ATGAAAACTCTACCTGCAACAACTCCGCAGGCGGCGAAGCTATGTCTGTTGCCCGTGGCAGTGTGGCAAATGCTGCTTGC
ACGCCTGCTGGAACAACATTATGGCCTGACACTCAACGACACGCCATTCAGTGATGAAACGGTAATTCAGGAACATATCG
ATGCCGGTATATCTTTGGCCGATGCCGTTAATTTTCTGGTGGAAAAGTACGGGCTGGTTCGTATTGATCGCAGGGGATTC
AACTGGCAAGAACAGTCCCCTTATCTGCGGGCGGTCGATATTCTGCGGGCGCGACAGGCAACTGGTTTATTGAAAAGAAA
TCGTATTAGCGCGGCACGGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5065.02 Da        Isoelectric Point: 8.7942

>AT242783 WP_010374875.1 NZ_CP096138:3069986-3070138 [Xanthomonas prunicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT242783 NZ_OW967388:581392-581733 [Enterobacter cloacae]
ATGAAATCTACTGACTCAGAGAACGATTCATTTCTCAAGTGGGGTCTGAATCGTAATGTGACACCTTGCTTTGGCGCTCG
TCTGGTACAGGAGGGAAACCGGCTGCACTATCTAGCTGACCGGGTCAGTATCACCGGTAAGTTCAGCGAAGCAGAATGTC
TTAAGCTGGATGTGGCATTCCCACATTTTATCAGCCAGATGGAGTCGATGTTGACTACTGGTGGAATGAATCCTCGCCAT
GCCCACTGTGTCACCCTGTACCACAATGGTTTCACCTGCGAAGCCGATACCCTTGGCAGTTACGGCTACGTATACATCGC
CGTTTACCCCACTCAACGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A836P2V1

Antitoxin

Source ID Structure
AlphaFold DB A0A836P2N2

References