Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1220167..1220698 Replicon chromosome
Accession NZ_CP096120
Organism Acinetobacter portensis strain JNE5

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MZO21_RS06095 Protein ID WP_248103499.1
Coordinates 1220402..1220698 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MZO21_RS06090 Protein ID WP_248103496.1
Coordinates 1220167..1220412 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MZO21_RS06065 (MZO21_06065) 1216095..1216640 - 546 WP_154773068.1 lecithin retinol acyltransferase family protein -
MZO21_RS06070 (MZO21_06070) 1217324..1217809 - 486 WP_227557093.1 transposase -
MZO21_RS06075 (MZO21_06075) 1217857..1218162 - 306 WP_087547287.1 IS630 transposase-related protein -
MZO21_RS06080 (MZO21_06080) 1218398..1218622 - 225 WP_154773066.1 hypothetical protein -
MZO21_RS06085 (MZO21_06085) 1218864..1219946 - 1083 WP_248103495.1 tRNA (uridine(54)-C5)-methyltransferase TrmA -
MZO21_RS06090 (MZO21_06090) 1220167..1220412 + 246 WP_248103496.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MZO21_RS06095 (MZO21_06095) 1220402..1220698 + 297 WP_248103499.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MZO21_RS15090 1220932..1221066 + 135 WP_282455579.1 hypothetical protein -
MZO21_RS06100 (MZO21_06100) 1221142..1224894 - 3753 WP_248103502.1 trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase -
MZO21_RS06105 (MZO21_06105) 1225011..1225508 + 498 WP_154773063.1 Lrp/AsnC ligand binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1121942..1365604 243662


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(8-86)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-69)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11538.84 Da        Isoelectric Point: 10.5084

>T242770 WP_248103499.1 NZ_CP096120:1220402-1220698 [Acinetobacter portensis]
MTYKLLRHKEFTAEWEKLPSVIREQFKKKLAKIIKQPHVPKSLLRGNLAGCCYKIKLLKAGFRLVYQVRDDQVIILLVTV
GKREDNVVYVEAKKRIEE

Download         Length: 297 bp

>T242770 NZ_OW967264:59951-60367 [Citrobacter freundii]
ATGAAGAAAACCTGGATGCTCGACACTAACATCTGCTCGTTCATCATGCGCGAGCAGCCGGCAGCGGTGCTGAAGCGCCT
GGAGCAGGCGGTGCTGCGCGGTGATCGCATCGTGGTCTCGGCCGTGACGTACGCCGAGATGCGCTTCGGCGCCACCGGCC
CGAAGGCCTCGCCGCGCCATATTCAGCTGGTCGACGCGTTCTGCGCGCGCCTCGATGCTGTCCTGCCCTGGGACCGCGCC
GCGGTGGACGCCACGACGGACATCCGGGTGGCGCTGCGCCTCGCCGGGACGCCGATCGGCCCGAACGACACGGCCATTGC
CGGGCACGCCATCGCGGCCAGTGCCGTCCTGGTGACGAACAATGTGAGAGAGTTTGCGCGGGTCCCGGGCCTGATGCTGG
AAGACTGGGTAAAATAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9289.62 Da        Isoelectric Point: 4.3135

>AT242770 WP_248103496.1 NZ_CP096120:1220167-1220412 [Acinetobacter portensis]
MATVNFRVDEALKEKSYSVLKEQGIAPTEFFTNILEYIAETGKLPVQKALLSEDDIELLAVVRKRIHDSKEMYEEISLDD
L

Download         Length: 246 bp

>AT242770 NZ_OW967264:59724-59954 [Citrobacter freundii]
ATGCGCACAGTTTCTATATTTAAAAACGGCAATAACCGCGCCATCCGTCTGCCCCGGGACCTGGATTTTGACGGCGTCAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATCATTCTGCGTCCCGTCCGGCCGACCTGGGGCTCATTCGCGCAGCTGG
ACAGGGCCGATCCGGACTTTATGGCGGAGCGTGAGGATGTGGTCAGCGATGAAGGACGCTTTGAGCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References