Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 357099..357735 Replicon chromosome
Accession NZ_CP096120
Organism Acinetobacter portensis strain JNE5

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag MZO21_RS01810 Protein ID WP_154771872.1
Coordinates 357370..357735 (+) Length 122 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag MZO21_RS01805 Protein ID WP_154771871.1
Coordinates 357099..357359 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MZO21_RS01770 (MZO21_01765) 352439..353758 + 1320 WP_171501184.1 preprotein translocase subunit SecY -
MZO21_RS01775 (MZO21_01770) 353779..353895 + 117 WP_000867907.1 50S ribosomal protein L36 -
MZO21_RS01780 (MZO21_01775) 354002..354358 + 357 WP_154771868.1 30S ribosomal protein S13 -
MZO21_RS01785 (MZO21_01780) 354378..354764 + 387 WP_001040166.1 30S ribosomal protein S11 -
MZO21_RS01790 (MZO21_01785) 354777..355403 + 627 WP_154771869.1 30S ribosomal protein S4 -
MZO21_RS01795 (MZO21_01790) 355420..356427 + 1008 WP_154771870.1 DNA-directed RNA polymerase subunit alpha -
MZO21_RS01800 (MZO21_01795) 356446..356811 + 366 WP_034587447.1 50S ribosomal protein L17 -
MZO21_RS01805 (MZO21_01800) 357099..357359 + 261 WP_154771871.1 succinate dehydrogenase assembly factor 2 Antitoxin
MZO21_RS01810 (MZO21_01805) 357370..357735 + 366 WP_154771872.1 hypothetical protein Toxin
MZO21_RS01815 (MZO21_01810) 357963..358841 - 879 WP_248102007.1 DMT family transporter -
MZO21_RS01820 (MZO21_01815) 358898..359323 - 426 WP_154771874.1 hypothetical protein -
MZO21_RS01825 (MZO21_01820) 359340..359555 - 216 WP_154771875.1 YheV family putative zinc ribbon protein -
MZO21_RS01830 (MZO21_01825) 359598..361625 - 2028 WP_154771876.1 M3 family metallopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-80)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 14645.71 Da        Isoelectric Point: 10.3936

>T242769 WP_154771872.1 NZ_CP096120:357370-357735 [Acinetobacter portensis]
MKHSRISIVFQLVIILLIIFILYQLLNILFLIFSIILLVISFLFFNKKEKIEYLAYLDDDVWSLKFKNNKEIYRVGIKNI
LNHQLYVVVQFKQSEQKPIVIWFDQLNRTQWKNLKVLSVLK

Download         Length: 366 bp

>T242769 NZ_OW967264:c43891-43586 [Citrobacter freundii]
ATGCAGTTTAAGGTTTACGCCTATAAAAGAGAAAGCCGCTACCGTCTGTTCGTCGACGTGCAGAGTGACATTATTGACAC
CCCGGGACGCCGGATGGTGATCCCGCTGGTCAGCGCCCGCCTGCTGTCCGACAAAGTCTCGCGTGAGCTTTATCCGGTGG
TGTCAGTCGGAGGTGACCCTTATCGTCTGATGACCACGGATATGGCCAGTGTGCCGGCCACTGTCATCGGGGAAGAAGTG
GCCGATCTCAGCCACCTGGAGAATGACATCCAGAACGCCATCAACCTGATGTTCCGGGGGATCTGA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 10435.96 Da        Isoelectric Point: 4.5235

>AT242769 WP_154771871.1 NZ_CP096120:357099-357359 [Acinetobacter portensis]
MTEEISLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADVEEKEMFNELVAQEDPDLLDWFMEVSEPPRPELKDFIKKLK
FYVHGA

Download         Length: 261 bp

>AT242769 NZ_OW967264:c44111-43893 [Citrobacter freundii]
GTGAAGCAGCGTATTACAGTGACAGTGGACAGCGACAGCTATCAGTTGCTCAAGGCATACGACGTAAATATCTCCGGTCT
GGTCAGTACGACCATGCAGAACGAAGCCCGCCGTCTGCGCGCCGAACGCTGGCAGGAAGAAAACCGGGAAGGTATGGCTG
AGGTGGCCAGCTTTATCGAGGCTAACGGATCGTTTGCTGACGAAAACAGGGACTGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References