Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mazEF/PRK09907-MazE |
Location | 4293569..4294143 | Replicon | chromosome |
Accession | NZ_CP096040 | ||
Organism | Caulobacter segnis strain RL271 |
Toxin (Protein)
Gene name | mazF | Uniprot ID | - |
Locus tag | MZV50_RS20015 | Protein ID | WP_252631031.1 |
Coordinates | 4293569..4293904 (-) | Length | 112 a.a. |
Antitoxin (Protein)
Gene name | mazE | Uniprot ID | - |
Locus tag | MZV50_RS20020 | Protein ID | WP_252631032.1 |
Coordinates | 4293901..4294143 (-) | Length | 81 a.a. |
Genomic Context
Location: 4289144..4289485 (342 bp)
Type: Others
Protein ID: WP_252631027.1
Type: Others
Protein ID: WP_252631027.1
Location: 4289492..4290862 (1371 bp)
Type: Others
Protein ID: WP_252631028.1
Type: Others
Protein ID: WP_252631028.1
Location: 4291023..4292378 (1356 bp)
Type: Others
Protein ID: WP_252635281.1
Type: Others
Protein ID: WP_252635281.1
Location: 4292418..4293095 (678 bp)
Type: Others
Protein ID: WP_252631029.1
Type: Others
Protein ID: WP_252631029.1
Location: 4293105..4293431 (327 bp)
Type: Others
Protein ID: WP_252631030.1
Type: Others
Protein ID: WP_252631030.1
Location: 4293569..4293904 (336 bp)
Type: Toxin
Protein ID: WP_252631031.1
Type: Toxin
Protein ID: WP_252631031.1
Location: 4293901..4294143 (243 bp)
Type: Antitoxin
Protein ID: WP_252631032.1
Type: Antitoxin
Protein ID: WP_252631032.1
Location: 4294206..4296788 (2583 bp)
Type: Others
Protein ID: WP_252631033.1
Type: Others
Protein ID: WP_252631033.1
Location: 4296988..4297929 (942 bp)
Type: Others
Protein ID: WP_252631034.1
Type: Others
Protein ID: WP_252631034.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MZV50_RS19990 (MZV50_19985) | 4289144..4289485 | + | 342 | WP_252631027.1 | GFA family protein | - |
MZV50_RS19995 (MZV50_19990) | 4289492..4290862 | - | 1371 | WP_252631028.1 | hypothetical protein | - |
MZV50_RS20000 (MZV50_19995) | 4291023..4292378 | - | 1356 | WP_252635281.1 | ATP-binding protein | - |
MZV50_RS20005 (MZV50_20000) | 4292418..4293095 | - | 678 | WP_252631029.1 | response regulator transcription factor | - |
MZV50_RS20010 (MZV50_20005) | 4293105..4293431 | - | 327 | WP_252631030.1 | PepSY domain-containing protein | - |
MZV50_RS20015 (MZV50_20010) | 4293569..4293904 | - | 336 | WP_252631031.1 | endoribonuclease MazF | Toxin |
MZV50_RS20020 (MZV50_20015) | 4293901..4294143 | - | 243 | WP_252631032.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
MZV50_RS20025 (MZV50_20020) | 4294206..4296788 | - | 2583 | WP_252631033.1 | TonB-dependent receptor | - |
MZV50_RS20030 (MZV50_20025) | 4296988..4297929 | - | 942 | WP_252631034.1 | DnaJ C-terminal domain-containing protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 112 a.a. Molecular weight: 11893.88 Da Isoelectric Point: 9.9687
>T242730 WP_252631031.1 NZ_CP096040:c4293904-4293569 [Caulobacter segnis]
VSARYVPDAGDIVWLQFDPQAGHEQAGHRPALVLSPAAYNGKRGMMLCCPMTSRIKGYPFEVVVPGVSPSAVLADQIKSV
DWVARRAARKDVAPPGVLAETRAKLKALLSV
VSARYVPDAGDIVWLQFDPQAGHEQAGHRPALVLSPAAYNGKRGMMLCCPMTSRIKGYPFEVVVPGVSPSAVLADQIKSV
DWVARRAARKDVAPPGVLAETRAKLKALLSV
Download Length: 336 bp
>T242730 NZ_OW967003:c2571369-2571019 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGGTGAGGTGGTGGAAGAGGC
GTTATTACGTTTGCAGGCGGTGGTGGAATAA
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGGTGAGGTGGTGGAAGAGGC
GTTATTACGTTTGCAGGCGGTGGTGGAATAA
Antitoxin
Download Length: 81 a.a. Molecular weight: 8949.12 Da Isoelectric Point: 4.1839
>AT242730 WP_252631032.1 NZ_CP096040:c4294143-4293901 [Caulobacter segnis]
MHVVVKKWGNSASVRIPARVMAAADLSIDQAVDVREENGRIIIEPIREPEYDLDAMLAEMEPDTFHEDVDFGAPAGKEVW
MHVVVKKWGNSASVRIPARVMAAADLSIDQAVDVREENGRIIIEPIREPEYDLDAMLAEMEPDTFHEDVDFGAPAGKEVW
Download Length: 243 bp
>AT242730 NZ_OW967003:c2571614-2571363 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTTCAGGTATGGTCATTCCTAATGTTGTGATGAAAGAACTTAACTTACG
GCCGGGGCAGAGCGTGGAGGCGCAAGTGAGCAACAATCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCACGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA
ATGCGTATTACCATAAAAAGATGGGGGAACAGTTCAGGTATGGTCATTCCTAATGTTGTGATGAAAGAACTTAACTTACG
GCCGGGGCAGAGCGTGGAGGCGCAAGTGAGCAACAATCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCACGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA