Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 4293569..4294143 Replicon chromosome
Accession NZ_CP096040
Organism Caulobacter segnis strain RL271

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag MZV50_RS20015 Protein ID WP_252631031.1
Coordinates 4293569..4293904 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag MZV50_RS20020 Protein ID WP_252631032.1
Coordinates 4293901..4294143 (-) Length 81 a.a.

Genomic Context


MZV50_RS19990MZV50_RS19995MZV50_RS20000MZV50_RS20005MZV50_RS20010MZV50_RS20015MZV50_RS20020MZV50_RS20025MZV50_RS20030
Location: 4289144..4289485 (342 bp)
Type: Others
Protein ID: WP_252631027.1
Location: 4289492..4290862 (1371 bp)
Type: Others
Protein ID: WP_252631028.1
Location: 4291023..4292378 (1356 bp)
Type: Others
Protein ID: WP_252635281.1
Location: 4292418..4293095 (678 bp)
Type: Others
Protein ID: WP_252631029.1
Location: 4293105..4293431 (327 bp)
Type: Others
Protein ID: WP_252631030.1
Location: 4293569..4293904 (336 bp)
Type: Toxin
Protein ID: WP_252631031.1
Location: 4293901..4294143 (243 bp)
Type: Antitoxin
Protein ID: WP_252631032.1
Location: 4294206..4296788 (2583 bp)
Type: Others
Protein ID: WP_252631033.1
Location: 4296988..4297929 (942 bp)
Type: Others
Protein ID: WP_252631034.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MZV50_RS19990 (MZV50_19985)4289144..4289485+342WP_252631027.1GFA family protein-
MZV50_RS19995 (MZV50_19990)4289492..4290862-1371WP_252631028.1hypothetical protein-
MZV50_RS20000 (MZV50_19995)4291023..4292378-1356WP_252635281.1ATP-binding protein-
MZV50_RS20005 (MZV50_20000)4292418..4293095-678WP_252631029.1response regulator transcription factor-
MZV50_RS20010 (MZV50_20005)4293105..4293431-327WP_252631030.1PepSY domain-containing protein-
MZV50_RS20015 (MZV50_20010)4293569..4293904-336WP_252631031.1endoribonuclease MazFToxin
MZV50_RS20020 (MZV50_20015)4293901..4294143-243WP_252631032.1AbrB/MazE/SpoVT family DNA-binding domain-containing proteinAntitoxin
MZV50_RS20025 (MZV50_20020)4294206..4296788-2583WP_252631033.1TonB-dependent receptor-
MZV50_RS20030 (MZV50_20025)4296988..4297929-942WP_252631034.1DnaJ C-terminal domain-containing protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(9-108)

Antitoxin

(1-80)


Sequences


Toxin        


Download         Length: 112 a.a.        Molecular weight: 11893.88 Da        Isoelectric Point: 9.9687

>T242730 WP_252631031.1 NZ_CP096040:c4293904-4293569 [Caulobacter segnis]
VSARYVPDAGDIVWLQFDPQAGHEQAGHRPALVLSPAAYNGKRGMMLCCPMTSRIKGYPFEVVVPGVSPSAVLADQIKSV
DWVARRAARKDVAPPGVLAETRAKLKALLSV

Download         Length: 336 bp

>T242730 NZ_OW967003:c2571369-2571019 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGGTGAGGTGGTGGAAGAGGC
GTTATTACGTTTGCAGGCGGTGGTGGAATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8949.12 Da        Isoelectric Point: 4.1839

>AT242730 WP_252631032.1 NZ_CP096040:c4294143-4293901 [Caulobacter segnis]
MHVVVKKWGNSASVRIPARVMAAADLSIDQAVDVREENGRIIIEPIREPEYDLDAMLAEMEPDTFHEDVDFGAPAGKEVW

Download         Length: 243 bp

>AT242730 NZ_OW967003:c2571614-2571363 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTTCAGGTATGGTCATTCCTAATGTTGTGATGAAAGAACTTAACTTACG
GCCGGGGCAGAGCGTGGAGGCGCAAGTGAGCAACAATCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCACGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References