Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1104836..1105281 Replicon chromosome
Accession NZ_CP096040
Organism Caulobacter segnis strain RL271

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MZV50_RS05445 Protein ID WP_252633403.1
Coordinates 1104836..1105111 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MZV50_RS05450 Protein ID WP_252633404.1
Coordinates 1105099..1105281 (-) Length 61 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MZV50_RS05420 (MZV50_05420) 1100213..1101133 + 921 WP_252633399.1 ABC transporter permease -
MZV50_RS05425 (MZV50_05425) 1101305..1102168 + 864 WP_252633400.1 ABC transporter permease -
MZV50_RS05430 (MZV50_05430) 1102165..1103283 + 1119 WP_252633401.1 ABC transporter ATP-binding protein -
MZV50_RS05435 (MZV50_05435) 1103294..1103408 - 115 Protein_1074 hypothetical protein -
MZV50_RS05440 (MZV50_05440) 1103430..1104833 + 1404 WP_252633402.1 aspartate aminotransferase family protein -
MZV50_RS05445 (MZV50_05445) 1104836..1105111 - 276 WP_252633403.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MZV50_RS05450 (MZV50_05450) 1105099..1105281 - 183 WP_252633404.1 antitoxin Antitoxin
MZV50_RS05455 (MZV50_05455) 1105345..1106745 + 1401 WP_252633406.1 glutamine synthetase family protein -
MZV50_RS05460 (MZV50_05460) 1106738..1108008 + 1271 Protein_1079 FAD-binding oxidoreductase -
MZV50_RS05465 (MZV50_05465) 1108011..1110031 + 2021 Protein_1080 sulfotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10110.58 Da        Isoelectric Point: 11.7386

>T242728 WP_252633403.1 NZ_CP096040:c1105111-1104836 [Caulobacter segnis]
VAQVIWTDQALADIDAIVTYISNQSRPLAAQRLGHRLFAAGESLADHPERGRLSTRGRREIAAVPPYVLRYRVVGDRVVI
GSVRHSARRPL

Download         Length: 276 bp

>T242728 NZ_OW967003:c2295869-2295555 [Escherichia coli]
ATGCAATTTACGGTATACCGCAGTCGCGGCAGGAACGCCGCGTTTCCCTTTGTTATCGATGTTACCAGCGACATTATTGG
TGAGATTAATCGCCGTATCGTTATTCCATTAACACCTATTGAACGATTTAGCCGTATTCGCCCACCAGAACGGCTTAATC
CAATCCTTTTACTGGTAGATGGCAAAGAATATGTGCTCATGACGCATGAGACTGCAACTGTTCCAGTTAACGCGCTGGGA
ACGAAATTTTGCGATGCCAGCGCACACCGAACGTTGATTAAAGGAGCATTAGATTTTATGCTCGACGGGATTTAA

Antitoxin


Download         Length: 61 a.a.        Molecular weight: 6761.45 Da        Isoelectric Point: 4.0075

>AT242728 WP_252633404.1 NZ_CP096040:c1105281-1105099 [Caulobacter segnis]
MAEPEPEIFDELEDEAELAADAAADADLEAGRVVPHERVREWLKSLGTPNQLPTPYSWRK

Download         Length: 183 bp

>AT242728 NZ_OW967003:c2296105-2295872 [Escherichia coli]
ATGACTGCAAAACGTACCACACAAAGTGTGACCGTCACCGTCGACCGTGAGTTAGTCAATCGCGCTCGTGATGCAGGCTT
AAATATGAGCGCCACCCTTACGGTTGCGCTCAATGCTGAACTTAAAAAACATGCAGCAACACGTTGGCGTGAAGAGAACA
CAGAAGCTATCGCTGCGTTAAATCAATTGGCTGATGAAACCGGATGTTTCTCTGATGAGTACCGGAGCTTCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References