Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 4317247..4317757 Replicon chromosome
Accession NZ_CP096018
Organism Alkalimarinus coralli strain SCSIO 12817

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag MY525_RS19510 Protein ID WP_250657524.1
Coordinates 4317494..4317757 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag MY525_RS19505 Protein ID WP_250657523.1
Coordinates 4317247..4317501 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MY525_RS19480 4313121..4313765 + 645 WP_250657518.1 DUF5610 domain-containing protein -
MY525_RS19485 4313880..4314551 + 672 WP_250657519.1 hypothetical protein -
MY525_RS19490 4314691..4315092 + 402 WP_250657520.1 DUF4345 family protein -
MY525_RS19495 4315141..4315806 - 666 WP_250657521.1 Frag1/DRAM/Sfk1 family protein -
MY525_RS19500 4316054..4316689 + 636 WP_250657522.1 glutathione S-transferase family protein -
MY525_RS19505 4317247..4317501 + 255 WP_250657523.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
MY525_RS19510 4317494..4317757 + 264 WP_250657524.1 Txe/YoeB family addiction module toxin Toxin
MY525_RS19515 4318332..4318805 + 474 WP_250657525.1 GNAT family N-acetyltransferase -
MY525_RS19520 4318828..4319346 + 519 WP_250657526.1 GNAT family N-acetyltransferase -
MY525_RS19525 4319561..4320004 + 444 WP_250657527.1 hypothetical protein -
MY525_RS19530 4320074..4320712 + 639 WP_250657528.1 hypothetical protein -
MY525_RS19535 4320823..4321065 + 243 WP_250657529.1 DUF4282 domain-containing protein -
MY525_RS19540 4321147..4321554 + 408 WP_250657530.1 DUF4345 domain-containing protein -
MY525_RS19545 4321700..4322398 + 699 WP_250657531.1 TIGR02117 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10321.72 Da        Isoelectric Point: 9.3455

>T242719 WP_250657524.1 NZ_CP096018:4317494-4317757 [Alkalimarinus coralli]
MSSRLLVWTDEAWSDYLYWQGQDKKTLKRINKLISDSKRAPFEGIGKPEPLKEYLSGFWSRRIDDTNRLVYAVDNTSLTV
ISCRYHY

Download         Length: 264 bp

>T242719 NZ_OW967003:320912-321015 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9322.51 Da        Isoelectric Point: 5.0481

>AT242719 WP_250657523.1 NZ_CP096018:4317247-4317501 [Alkalimarinus coralli]
MKIVSFTEARNGLKAVLDSVVNDADSAIITRRDSEDAVVMSLNYYNSLMETVHLLRSPANAEHLAKSIDQFRKGSATPRD
LIDE

Download         Length: 255 bp

>AT242719 NZ_OW967003:c321053-320782 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References