Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1579314..1579876 Replicon chromosome
Accession NZ_CP096018
Organism Alkalimarinus coralli strain SCSIO 12817

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag MY525_RS07165 Protein ID WP_250655205.1
Coordinates 1579562..1579876 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag MY525_RS07160 Protein ID WP_250655204.1
Coordinates 1579314..1579562 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MY525_RS07130 1576902..1577117 - 216 WP_045857757.1 helix-turn-helix domain-containing protein -
MY525_RS07135 1577377..1577625 - 249 WP_250655199.1 helix-turn-helix domain-containing protein -
MY525_RS07140 1577706..1578008 + 303 WP_250655200.1 type II toxin-antitoxin system HigB family toxin -
MY525_RS07145 1578101..1578469 + 369 WP_250655201.1 transcriptional regulator -
MY525_RS07150 1578462..1578794 + 333 WP_250655202.1 hypothetical protein -
MY525_RS07155 1578854..1579168 + 315 WP_250655203.1 hypothetical protein -
MY525_RS07160 1579314..1579562 + 249 WP_250655204.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
MY525_RS07165 1579562..1579876 + 315 WP_250655205.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MY525_RS07170 1580073..1580255 - 183 WP_250655206.1 hypothetical protein -
MY525_RS07175 1580255..1580530 - 276 WP_250655207.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
MY525_RS07180 1580731..1581195 - 465 WP_250655208.1 M15 family metallopeptidase -
MY525_RS07185 1581587..1582294 + 708 WP_250655209.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-96)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 12339.05 Da        Isoelectric Point: 9.6406

>T242714 WP_250655205.1 NZ_CP096018:1579562-1579876 [Alkalimarinus coralli]
VKQKINSKVRVTPRARDDLKNIGRYTEQTWGKTQRNRYLKSIDARFHWLAENPQLGKHRTDICEEYYSFPEGQHVVFYLI
GRNSIDIIGIPHKEMDIISYFLEG

Download         Length: 315 bp

>T242714 NZ_OW849527:c4935273-4934899 [Citrobacter freundii]
ATGGTCAAAGGATCCGCGCTTTTTGATACCAACATCCTCATCGATCTGTTTAGTGGGAGAAATGAAGCAAAACTAGCGAT
AGAAACATGGCCGCCGCAGAATGCAATCAGCCTCATTACATGGATGGAGGTGATGGTGGGTGCAAAAAAATACCATCAGG
AAGCCCGTACTCGTGTTGCGCTAGGTGCTTTTAACGTGATCGGCGTTTCACAGGATATTGCTGAACGAAGCGTGAGTATC
AGACAGGAATATGGGATGAAATTGCCGGATGCCATTATTTTGGCAACAGCACAGATTCATCGTCTTACGCTGGTTACGCG
AAATACTAAGGATTTTGCAGGCCTATCCGGTGTGGTCACACCGTATACATTATAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9007.90 Da        Isoelectric Point: 4.3431

>AT242714 WP_250655204.1 NZ_CP096018:1579314-1579562 [Alkalimarinus coralli]
MATTSLSLGEHWEVFIKNEISSGRYGSASEVVRDALRAMEERKSKLEALRSHLAEGATQASNGDFVDNFSMDSLINDLDA
ET

Download         Length: 249 bp

>AT242714 NZ_OW849527:c4935515-4935273 [Citrobacter freundii]
ATGATGGCTGGGATGGATATGGGCAGAATTTTACTCGATTTATCAGATGAAGTGATTAAACGTCTTGATGATCTCAAGGT
GCAGCGCAACCTGCCGCGAGCAGAACTTTTACGGGAGGCCGTTGAACAGTATCTTGAGAGACAGGATCAGGCTGAAACCA
CAATTTCACGTGCTCTTGGGCTGTGGCAAGGCTGTGAGGAAGATGGTGTTGAATACCAGCGTAAACTCCGTGAGGAATGG
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References