Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 1200481..1201037 Replicon chromosome
Accession NZ_CP096018
Organism Alkalimarinus coralli strain SCSIO 12817

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MY525_RS05305 Protein ID WP_250654857.1
Coordinates 1200481..1200792 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MY525_RS05310 Protein ID WP_250654858.1
Coordinates 1200780..1201037 (-) Length 86 a.a.

Genomic Context

MY525_RS05285MY525_RS05290MY525_RS05295MY525_RS05300MY525_RS05325MY525_RS05330MY525_RS05305MY525_RS05310MY525_RS05315MY525_RS05320MY525_RS05335MY525_RS05340MY525_RS05345
Location: 1196221..1197240 (1020 bp)
Type: Others
Protein ID: WP_250654853.1
Location: 1197237..1197719 (483 bp)
Type: Others
Protein ID: WP_250654854.1
Location: 1197716..1198558 (843 bp)
Type: Others
Protein ID: WP_250654855.1
Location: 1198657..1200285 (1629 bp)
Type: Others
Protein ID: WP_250654856.1
Location: 1202169..1202405 (237 bp)
Type: Others
Protein ID: WP_250654861.1
Location: 1202410..1202721 (312 bp)
Type: Others
Protein ID: WP_250654862.1
Location: 1200481..1200792 (312 bp)
Type: Toxin
Protein ID: WP_250654857.1
Location: 1200780..1201037 (258 bp)
Type: Antitoxin
Protein ID: WP_250654858.1
Location: 1201119..1201370 (252 bp)
Type: Others
Protein ID: WP_250654859.1
Location: 1201360..1201623 (264 bp)
Type: Others
Protein ID: WP_250654860.1
Location: 1202982..1203284 (303 bp)
Type: Others
Protein ID: WP_250654863.1
Location: 1203281..1203559 (279 bp)
Type: Others
Protein ID: WP_250654864.1
Location: 1204150..1204620 (471 bp)
Type: Others
Protein ID: WP_250654865.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MY525_RS052851196221..1197240+1020WP_250654853.1PhoH family protein-
MY525_RS052901197237..1197719+483WP_250654854.1rRNA maturation RNase YbeY-
MY525_RS052951197716..1198558+843WP_250654855.1transporter associated domain-containing protein-
MY525_RS053001198657..1200285+1629WP_250654856.1apolipoprotein N-acyltransferase-
MY525_RS053051200481..1200792-312WP_250654857.1type II toxin-antitoxin system RelE/ParE family toxinToxin
MY525_RS053101200780..1201037-258WP_250654858.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
MY525_RS053151201119..1201370-252WP_250654859.1CopG family transcriptional regulator-
MY525_RS053201201360..1201623-264WP_250654860.1BrnT family toxin-
MY525_RS053251202169..1202405+237WP_250654861.1addiction module protein-
MY525_RS053301202410..1202721+312WP_250654862.1type II toxin-antitoxin system RelE/ParE family toxin-
MY525_RS053351202982..1203284-303WP_250654863.1hypothetical protein-
MY525_RS053401203281..1203559-279WP_250654864.1BrnT family toxin-
MY525_RS053451204150..1204620-471WP_250654865.1GNAT family N-acetyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegron--1198657..12032844627


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11937.56 Da        Isoelectric Point: 4.5858

>T242712 WP_250654857.1 NZ_CP096018:c1200792-1200481 [Alkalimarinus coralli]
MAQIIWTEPALNDLNDIAEYIAVSNPYAAKQLVENVFSNVQRLEQFPDSGRVPDEISNLNYREVVVNPCRVFYKIDMDSV
YILHVMRQERDLRKFLLSTTNGS

Download         Length: 312 bp

>T242712 NZ_OW849527:c4527118-4526834 [Citrobacter freundii]
ATGACTTATGAACTGGAATTCGACCCGAGAGCCTTAAAAGAGTGGCATAAACTGGGTGATACGGTGAAGGCTCAGTTTAA
GAAGAAGTTGGCCGACGTGTTGTTGAACCCCAGAATTGACTCTGCCCGTTTAAACGGTCTTCCAGATTGCTATAAAATTA
AGCTTAAATCGTCCGGCTATCGTCTGGTGTACCAGGTTCGGGATGAGGTTGTGACCGTGTTTGTTGTCGCGGTCGGCAAG
CGACAACATTCGGCCGTTTATCTCGATGCAAACAAACGGCTTTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9713.35 Da        Isoelectric Point: 8.5371

>AT242712 WP_250654858.1 NZ_CP096018:c1201037-1200780 [Alkalimarinus coralli]
MRTEVVTTLKRQATKLLADLHESKEPILITEHGQPSAYLLDVADYELMVNRMKILEGIAKGEQAIRDGRTMDMGQAKDKM
NKWLK

Download         Length: 258 bp

>AT242712 NZ_OW849527:c4527350-4527108 [Citrobacter freundii]
ATGGCCACGCTGAACGTCCGTCTGGATGACAAACTCAAAAATGAGGCTTATGCCGTGCTGGAAAAACTGAACATTACTCC
AACGGAAGCTGTGCGATTACTGTTTCAGTACGTCGCGGAAACGGGGCGCATGCCAGTGAAAACCGTCACCGTTAGCGACA
GCGAAGATACACTGATTCAGACAGTCCGGGAGAGGCTGGCCAGCCCGCAAAAAGGAATCAAGGTTAGTCTGGATGACTTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References