Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 182585..183151 Replicon chromosome
Accession NZ_CP096018
Organism Alkalimarinus coralli strain SCSIO 12817

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MY525_RS00840 Protein ID WP_250658091.1
Coordinates 182585..182869 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MY525_RS00845 Protein ID WP_250658092.1
Coordinates 182873..183151 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MY525_RS00810 178301..178531 + 231 WP_250658085.1 hypothetical protein -
MY525_RS00815 178531..178923 + 393 WP_250658086.1 type II toxin-antitoxin system VapC family toxin -
MY525_RS00820 179213..179761 + 549 WP_250658087.1 hypothetical protein -
MY525_RS00830 181126..181545 + 420 WP_250658089.1 hypothetical protein -
MY525_RS00835 181885..182367 + 483 WP_250658090.1 hypothetical protein -
MY525_RS00840 182585..182869 - 285 WP_250658091.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MY525_RS00845 182873..183151 - 279 WP_250658092.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MY525_RS00850 183492..183995 + 504 WP_250658093.1 hypothetical protein -
MY525_RS00855 184062..184433 + 372 WP_250658094.1 helix-turn-helix domain-containing protein -
MY525_RS00860 184644..185600 - 957 WP_250658095.1 PA2778 family cysteine peptidase -
MY525_RS00865 185654..186058 - 405 WP_250658096.1 PA2779 family protein -
MY525_RS00870 186373..187821 - 1449 WP_250658097.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-44)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11183.95 Da        Isoelectric Point: 6.4718

>T242710 WP_250658091.1 NZ_CP096018:c182869-182585 [Alkalimarinus coralli]
VIYWEEESLNDRERIFEFLYDFNPIAAEKTDKIIEEKVENLHQQPLMGVQRGGIQGRLLVIPEISMIVSYWTDNTVIRVM
RVLHQKQKFPAKRP

Download         Length: 285 bp

>T242710 NZ_OW849527:3810348-3810566 [Citrobacter freundii]
ATGTCCGATAAACCATTAACTAAAACAGATTATTTGATGCGCCTGCGACGTTGCCAGACAATTGATACGCTAGAGCGCGT
TATTGAAAAAAATAAATATGAATTGTCCGACAACGAACTGGCTGTATTTTACTCAGCAGCAGATCATCGCCTTGCTGAAT
TGACCATGAATAAGCTTTACGACAAGATTCCAACTTCTGTTTGGAAATTCATTCGCTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10885.07 Da        Isoelectric Point: 7.8949

>AT242710 WP_250658092.1 NZ_CP096018:c183151-182873 [Alkalimarinus coralli]
MDTRVQFRIDEETKRLAQQRTESQGRTLSDACRELTEQLADQQRKATSHDAWLTEQVNLAFEKFQTNRSTFVEHEHAKSS
MSERKAKIRERC

Download         Length: 279 bp

>AT242710 NZ_OW849527:3809946-3810320 [Citrobacter freundii]
ATGGATGAATACTCACCCAAAAGACATGATATCGCGCAGCTTAAATTTCTCTGCGAAACTCTGTATCATGACTGTCTTGC
AAACCTTGAACAAAGTAACCATGGCTGGGTTAATGACCCTACCTCTGCAACCAGCTTGCAGCTCAATGAACTGATAGAGC
ATATTGCAACCTTCGCACTTAATTATAAAATTAAGTACAATGAGGACAATAAGCTGATCGCGCAGATAGATGAATACCTG
GATGACACTTTTATGTTGTTCAGCAGTTATGGTATTAATACGCAGGATCTGCAGAAATGGCGGAAGTCAGGTAATCGACT
GTTTCGCTGTTTTGTCAATGCCACCAGGGCTAATCCTGTTAGTTTGTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References