242706

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 2914432..2914937 Replicon chromosome
Accession NZ_CP096017
Organism Alkalimarinus coralli strain SCSIO 12638

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MY524_RS13255 Protein ID WP_250656356.1
Coordinates 2914432..2914689 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag MY524_RS13260 Protein ID WP_250656357.1
Coordinates 2914686..2914937 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MY524_RS13230 2909904..2910881 + 978 WP_250656351.1 putative DNA binding domain-containing protein -
MY524_RS13235 2910970..2913033 - 2064 WP_250656352.1 MFS transporter -
MY524_RS13240 2913253..2913618 - 366 WP_250656353.1 type II toxin-antitoxin system RelE/ParE family toxin -
MY524_RS13245 2913623..2913889 - 267 WP_250656354.1 hypothetical protein -
MY524_RS13250 2914023..2914205 + 183 WP_250656355.1 hypothetical protein -
MY524_RS13255 2914432..2914689 - 258 WP_250656356.1 Txe/YoeB family addiction module toxin Toxin
MY524_RS13260 2914686..2914937 - 252 WP_250656357.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
MY524_RS13265 2915423..2915689 + 267 WP_250656358.1 ribbon-helix-helix protein, CopG family -
MY524_RS13270 2915686..2915973 + 288 WP_250656359.1 type II toxin-antitoxin system RelE/ParE family toxin -
MY524_RS13275 2916051..2916308 + 258 WP_250656360.1 hypothetical protein -
MY524_RS13280 2916373..2916513 + 141 WP_250656361.1 hypothetical protein -
MY524_RS13285 2916699..2917427 - 729 WP_250658854.1 amino acid ABC transporter ATP-binding protein -
MY524_RS13290 2917482..2918588 - 1107 WP_250656362.1 amino acid ABC transporter permease -
MY524_RS13295 2918599..2919810 - 1212 WP_250656363.1 ABC transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10246.82 Da        Isoelectric Point: 10.0297

>T242706 WP_250656356.1 NZ_CP096017:c2914689-2914432 [Alkalimarinus coralli]
MKVTFSSAAWDQYLYWQTTDKKILKRINQLIKDIKREPYEGIGKPEPLKHGLAGYWSRRINDEHRIVYKYTEGTILIAQL
RYHYT

Download         Length: 258 bp

>T242706 NZ_OW849527:284447-284722 [Citrobacter freundii]
ATGAAGGAAAAAGTGTTGTCTTTACGCAAAAAGCAAAAGAACACGCTGGATCAGCTTTTTAAAGCACCGACGCCGCAGGG
AATCAAGTGGTCGGAAATTGAGTCACTGATCAAGGCGTTAGGTGGCGAAATCAAAGAAGGACGAGGCTCGCGATGTAAAT
TTCTTTTAAATAAGAGCATTGCGAGTTTTCATAGACCACATCCTTCTCCGGATACAGATAAAGGCGCGGTCGAAAACGTA
CGTGACTGGTTAACAAGTATAGGGGTAAAACCATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9316.54 Da        Isoelectric Point: 4.4737

>AT242706 WP_250656357.1 NZ_CP096017:c2914937-2914686 [Alkalimarinus coralli]
MDAISYTHARANLSSTMEKVCNDHAPIIITRKSESPVVMMSLEDYQAMEETTYLLRSPANARQLLESIAELESGKGTERE
LLE

Download         Length: 252 bp

>AT242706 NZ_OW849527:284719-285078 [Citrobacter freundii]
ATGATCAAACCCAAAACGCCAAACTCAATGGAAATCGCCGGTCAACCTGCGGTAATTAATTATGTCCCTGAGCTTAATGC
GTTTCGCGGTAAGTTCCTGGGATTGTCAGGCTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAGGGGG
AGATCTCCTTACGAGAGTATCTTGATGATTGCTCTGCCGCAGGGATAGAACCTTACGCAAACCCGGAAAAGCTGAAGACG
TTTACTCTGCGCTATCCAGAGTCTTTCGGAGAACGTTTAAGTTTTGCGGCAGCGGAAGAACAGGTATCAGTCAATACATG
GATCATCGAAACGCTCAGCAAAAGTCTCAAACAGGCATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References