Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2766380..2766905 Replicon chromosome
Accession NZ_CP096017
Organism Alkalimarinus coralli strain SCSIO 12638

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MY524_RS12485 Protein ID WP_250656208.1
Coordinates 2766621..2766905 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MY524_RS12480 Protein ID WP_250656207.1
Coordinates 2766380..2766631 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MY524_RS12450 2761906..2762814 - 909 WP_250656201.1 LysR family transcriptional regulator -
MY524_RS12455 2762983..2763702 + 720 WP_250656202.1 glutathione S-transferase family protein -
MY524_RS12460 2763922..2764587 + 666 WP_250656203.1 SDR family oxidoreductase -
MY524_RS12465 2764679..2764933 + 255 WP_250656204.1 hypothetical protein -
MY524_RS12470 2764967..2765620 - 654 WP_250656205.1 CBS domain-containing protein -
MY524_RS12475 2765787..2766152 - 366 WP_250656206.1 YbaN family protein -
MY524_RS12480 2766380..2766631 + 252 WP_250656207.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MY524_RS12485 2766621..2766905 + 285 WP_250656208.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MY524_RS12490 2766993..2768525 - 1533 WP_250656209.1 methyl-accepting chemotaxis protein -
MY524_RS12495 2768721..2769215 + 495 WP_250656210.1 peptidylprolyl isomerase -
MY524_RS12500 2769431..2769838 + 408 WP_250656211.1 GFA family protein -
MY524_RS12505 2769924..2770952 + 1029 WP_250656212.1 DUF2157 domain-containing protein -
MY524_RS12510 2771027..2771689 + 663 WP_250656213.1 YoaK family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(11-77)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10847.91 Da        Isoelectric Point: 10.7024

>T242705 WP_250656208.1 NZ_CP096017:2766621-2766905 [Alkalimarinus coralli]
MTYKLKFLPAALKEWKKLASPIQSQFKKKLSERLENPRVPSAKLSGFDSVYKIKLRTAGYRLAYEVVDDEVVVYVLVVGK
RDKGKVYQKLKGRI

Download         Length: 285 bp

>T242705 NZ_OW849527:34610-34972 [Citrobacter freundii]
ATGTGGGAAGTGGAAACAACGGATGCTTTCGATAAATGGTTTGACGTACAGACCGAAGCGCTCAAGGAAGATATGCTCGC
AGCAATGATGATTTTATCCGAGTATGGTCCTCAGTTAGGCAGGCCGTTTGCTGATACGGTAAATGCTTCTGCTTTTTCAA
ATATGAAAGAGTTGCGAGTACAGCATCAGGGTAGTCCGATTCGGGCGTTCTTCGCGTTTGATCCTTCTCGCCATGGCATC
GTGCTATGCGCTGGAGATAAAACAGGGTTAAACGAAAAGAAATTCTATAAAGAGATGATCAGGCTTGCGGATGCTGAGTA
CCGAAATCACCTAATAAGTAAGGAAAATTATGGCTACCCTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9152.48 Da        Isoelectric Point: 4.2813

>AT242705 WP_250656207.1 NZ_CP096017:2766380-2766631 [Alkalimarinus coralli]
MRQVLADCSASISELKKNPTALLNESAGAPIAILNHNKPAAYLVPAETYEWLMDMLDDQELAKLVEQRVAKKDQAVEVSL
DDL

Download         Length: 252 bp

>AT242705 NZ_OW849527:34959-35258 [Citrobacter freundii]
ATGGCTACCCTTAAAGAATTGATGGCGAAACAAAGCCCGGAAAGCCAGGAGCGTATTACCGAAAAAGTAGAAATACTACG
TCAGGCGGTTGCGTTAAATATGTTAAGGGAAGAACTGAATCTCTCTCAGGCTGAACTTGCCTCGGCAATGGGGGTTAAGC
AGCCAACAATCGCAAAAATGGAGCAGGCAGATAACGATCCTCGTCTGTCGACGCTCAAGCGTTATGTCACGGCACTGGGT
GGTGAACTTAGCATTGATGTTAAGCTACCTACAGGTAAAAGAGTCGCGTTCTATCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References