Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1579016..1579578 Replicon chromosome
Accession NZ_CP096017
Organism Alkalimarinus coralli strain SCSIO 12638

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag MY524_RS07160 Protein ID WP_250655205.1
Coordinates 1579264..1579578 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag MY524_RS07155 Protein ID WP_250655204.1
Coordinates 1579016..1579264 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MY524_RS07125 1576604..1576819 - 216 WP_045857757.1 helix-turn-helix domain-containing protein -
MY524_RS07130 1577079..1577327 - 249 WP_250655199.1 helix-turn-helix domain-containing protein -
MY524_RS07135 1577408..1577710 + 303 WP_250655200.1 type II toxin-antitoxin system HigB family toxin -
MY524_RS07140 1577803..1578171 + 369 WP_250655201.1 transcriptional regulator -
MY524_RS07145 1578164..1578496 + 333 WP_250655202.1 hypothetical protein -
MY524_RS07150 1578556..1578870 + 315 WP_250655203.1 hypothetical protein -
MY524_RS07155 1579016..1579264 + 249 WP_250655204.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
MY524_RS07160 1579264..1579578 + 315 WP_250655205.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MY524_RS07165 1579775..1579957 - 183 WP_250655206.1 hypothetical protein -
MY524_RS07170 1579957..1580232 - 276 WP_250655207.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
MY524_RS07175 1580433..1580897 - 465 WP_250655208.1 M15 family metallopeptidase -
MY524_RS07180 1581289..1581996 + 708 WP_250655209.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-96)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 12339.05 Da        Isoelectric Point: 9.6406

>T242703 WP_250655205.1 NZ_CP096017:1579264-1579578 [Alkalimarinus coralli]
VKQKINSKVRVTPRARDDLKNIGRYTEQTWGKTQRNRYLKSIDARFHWLAENPQLGKHRTDICEEYYSFPEGQHVVFYLI
GRNSIDIIGIPHKEMDIISYFLEG

Download         Length: 315 bp

>T242703 NZ_OW849471:165097-165588 [Klebsiella oxytoca]
GTGGGCAAAGTAACGGCTCCGGTCCCACTCGGTACGTCACACATCCTCGCTGAGTTTCACTGTGGTGAGCCTGTACTGGA
CGAATGGATAAAGCACCGGGGACTAAAAAATCAGTCCCTGGGGGCGGCCAGAACGTTTGTGGTGTGCCGGGGAAATGCTT
CACAGGTGCTTGCCTACTACTCTCTCGCGACCGGCAGCGTCACTCATGCCATTGCGCCGGGAAGCCTGCGAAGGAATATG
CCCGATCCTGTACCTGTCATCATCCTGGCCCGTCTTGCTGTCGATACGAGTTATCACGGCCAGGGACTGGGGGCTGATTT
ACTGCATGATGCCGTATTACGTTGCTGTCGGGTGGCTGAGAACATTGGCGTGCGGGCCGTTATGGTTCATGCACTCTCTG
ACAGTGCCAGACAGTTCTACATACATCACGGATTTATCCCTTCACAAACGCAGGATAGAACCCTTTTTTTACGGTTGCCT
CTCATTACTTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9007.90 Da        Isoelectric Point: 4.3431

>AT242703 WP_250655204.1 NZ_CP096017:1579016-1579264 [Alkalimarinus coralli]
MATTSLSLGEHWEVFIKNEISSGRYGSASEVVRDALRAMEERKSKLEALRSHLAEGATQASNGDFVDNFSMDSLINDLDA
ET

Download         Length: 249 bp

>AT242703 NZ_OW849471:164843-165109 [Klebsiella oxytoca]
ATGAAATCTGATGTTCAGCTCAACATCCGGGCGAAAGAAGCCCAGCGGGCTCTGATTGATACTGCCGCTGAGATTCTCCA
CAAATCACGCACTGATTTTATACTGGAGATGGCCTGTCAGGCGGCGGAAAACGTCATTCTTGACCGCCGTATGTTCAATC
TCAATGATGAACAGTACGCCGAGTTTATCGACATGCTGGATGCGCCGGTCACCGCTAACCCGGCGATGGAGAAACTCCTG
GCGAGAAAACCGCAGTGGGCAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References