Detailed information of TA system TA242702

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 1200819..1201323
• Replicon: chromosome
• Accession: NZ_CP096017
• Organism: Alkalimarinus coralli strain SCSIO 12638

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: MY524_RS05310
• Protein ID: WP_250654860.1
• Coordinates: 1201060..1201323 (-)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: MY524_RS05305
• Protein ID: WP_250654859.1
• Coordinates: 1200819..1201070 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MY524_RS05275	1195921..1196940	+	1020	WP_250654853.1	PhoH family protein	-
MY524_RS05280	1196937..1197419	+	483	WP_250654854.1	rRNA maturation RNase YbeY	-
MY524_RS05285	1197416..1198258	+	843	WP_250654855.1	transporter associated domain-containing protein	-
MY524_RS05290	1198357..1199985	+	1629	WP_250654856.1	apolipoprotein N-acyltransferase	-
MY524_RS05295	1200181..1200492	-	312	WP_250654857.1	type II toxin-antitoxin system RelE/ParE family toxin	-
MY524_RS05300	1200480..1200737	-	258	WP_250654858.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
MY524_RS05305	1200819..1201070	-	252	WP_250654859.1	CopG family transcriptional regulator	Antitoxin
MY524_RS05310	1201060..1201323	-	264	WP_250654860.1	BrnT family toxin	Toxin
MY524_RS05315	1201869..1202105	+	237	WP_250654861.1	addiction module protein	-
MY524_RS05320	1202110..1202421	+	312	WP_250654862.1	type II toxin-antitoxin system RelE/ParE family toxin	-
MY524_RS05325	1202682..1202984	-	303	WP_250654863.1	hypothetical protein	-
MY524_RS05330	1202981..1203259	-	279	WP_250654864.1	BrnT family toxin	-
MY524_RS05335	1203850..1204320	-	471	WP_250654865.1	GNAT family N-acetyltransferase	-
MY524_RS05340	1204418..1205749	-	1332	WP_250654866.1	group II intron reverse transcriptase/maturase	-
MY524_RS05345	1205785..1205949	-	165	WP_250654867.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integron	-	-	1198357..1202984	4627

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (6-81)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10120.37 Da
• Isoelectric Point: 6.7196

>T242702 WP_250654860.1 NZ_CP096017:c1201323-1201060 [Alkalimarinus coralli]
MYNFEFDHKKSNSNLDKHGIDFNEAQSLWGDPDLIEIQAKSEDEPRSLVIGRIGEKHWSAVITCRKESIRIISVRRSRKT
EVALYES

Nucleotide

• Length: 264 bp

>T242702 NZ_OW849471:53921-54403 [Klebsiella oxytoca]
GTGGGACGTATAACCACGCCCGAGCCGTTATCCAGCTCTCATCAGCTGGCTGAGTTCGTCAGTGGAGAGACAGTCCTCGA
TGAATGGCTAAAACAGAGAGGTTTAAAAAATCAAGCTCTTGGCGCTGCCCGAACGTTCGTTGTTTGCAAGACGGGTACGA
AGCAAGTAGCTGGTTTTTACTCTTTGGCCACCGGTAGCGTTAACCATACGGAAGCGACAGGTAGTCTTCGGCGTAACATG
CCAGATCCTATACCGGTGATTATACTCGCTCGCCTGGCGGTAGATGTCTCATTGCACGGAAAAGGGGTTGGCGCCGATTT
ACTCCACGATGCAGTTCTACGGTGTTATCGCGTAGCTGAGAACATTGGGGTTCGTGCGATAATGGTTCATGCGCTTACTG
AAGAAGCCAAAGGTTTCTATGCTCACCATGGATTTAAGGCATCACAAACTCATGAGAGGACTCTGTTTCTAAAGCTTCCA
TGA

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9698.01 Da
• Isoelectric Point: 8.6572

>AT242702 WP_250654859.1 NZ_CP096017:c1201070-1200819 [Alkalimarinus coralli]
MKAKDFDKKFDNNEDIIDDLDLSSIKRPNQAQKRVNVDFPTWMIDSLDKEANRVGVTRQSIIKVWLAEKLEEQAANKALH
RTR

Nucleotide

• Length: 252 bp

>AT242702 NZ_OW849471:53667-53933 [Klebsiella oxytoca]
ATGAAATCAGATGTTCAACTCAACCTAAGAGCTAAAGAGTCTCAGAGAGCACTCATCGATGCTGCTGCAGAGATCCTTCA
TAAATCGCGAACCGACTTTATCCTGGAGATGGCCTGCAAGGCTGCGGAGAATGTGATCCTTGATCGCCGTGTTTTCAATT
TTAACGACGAACAGTATGCAGAGTTCATCGATATGCTCGATGCACCAGTCGAGGATGAGCCCGCCATTAATAAACTACTG
GCAAGGAAACCTCAGTGGGACGTATAA