Detailed information of TA system TA242699

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 183995..184561
• Replicon: chromosome
• Accession: NZ_CP096017
• Organism: Alkalimarinus coralli strain SCSIO 12638

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: MY524_RS00840
• Protein ID: WP_250658091.1
• Coordinates: 183995..184279 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: MY524_RS00845
• Protein ID: WP_250658092.1
• Coordinates: 184283..184561 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MY524_RS00810	179711..179941	+	231	WP_250658085.1	hypothetical protein	-
MY524_RS00815	179941..180333	+	393	WP_250658086.1	type II toxin-antitoxin system VapC family toxin	-
MY524_RS00820	180623..181171	+	549	WP_250658087.1	hypothetical protein	-
MY524_RS00830	182536..182955	+	420	WP_250658089.1	hypothetical protein	-
MY524_RS00835	183295..183777	+	483	WP_250658090.1	hypothetical protein	-
MY524_RS00840	183995..184279	-	285	WP_250658091.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
MY524_RS00845	184283..184561	-	279	WP_250658092.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
MY524_RS00850	184902..185405	+	504	WP_250658093.1	hypothetical protein	-
MY524_RS00855	185472..185843	+	372	WP_250658094.1	helix-turn-helix domain-containing protein	-
MY524_RS00860	186054..187010	-	957	WP_250658095.1	PA2778 family cysteine peptidase	-
MY524_RS00865	187064..187468	-	405	WP_250658096.1	PA2779 family protein	-
MY524_RS00870	187783..189231	-	1449	WP_250658097.1	aldehyde dehydrogenase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-89)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (5-44)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 11183.95 Da
• Isoelectric Point: 6.4718

>T242699 WP_250658091.1 NZ_CP096017:c184279-183995 [Alkalimarinus coralli]
VIYWEEESLNDRERIFEFLYDFNPIAAEKTDKIIEEKVENLHQQPLMGVQRGGIQGRLLVIPEISMIVSYWTDNTVIRVM
RVLHQKQKFPAKRP

Nucleotide

• Length: 285 bp

>T242699 NZ_OW849470:2195825-2195928 [Klebsiella oxytoca]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTTTTTTT

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10885.07 Da
• Isoelectric Point: 7.8949

>AT242699 WP_250658092.1 NZ_CP096017:c184561-184283 [Alkalimarinus coralli]
MDTRVQFRIDEETKRLAQQRTESQGRTLSDACRELTEQLADQQRKATSHDAWLTEQVNLAFEKFQTNRSTFVEHEHAKSS
MSERKAKIRERC

Nucleotide

• Length: 279 bp

>AT242699 NZ_OW849470:c2195935-2195790 [Klebsiella oxytoca]
AAAAGATAAAAAAAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGT