242696

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 4333598..4334103 Replicon chromosome
Accession NZ_CP096016
Organism Alkalimarinus coralli strain SCSIO 12582

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MY523_RS19545 Protein ID WP_250656356.1
Coordinates 4333598..4333855 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag MY523_RS19550 Protein ID WP_250656357.1
Coordinates 4333852..4334103 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MY523_RS19520 4329070..4330047 + 978 WP_250656351.1 putative DNA binding domain-containing protein -
MY523_RS19525 4330136..4332199 - 2064 WP_250656352.1 MFS transporter -
MY523_RS19530 4332419..4332784 - 366 WP_250656353.1 type II toxin-antitoxin system RelE/ParE family toxin -
MY523_RS19535 4332789..4333055 - 267 WP_250656354.1 hypothetical protein -
MY523_RS19540 4333189..4333371 + 183 WP_250656355.1 hypothetical protein -
MY523_RS19545 4333598..4333855 - 258 WP_250656356.1 Txe/YoeB family addiction module toxin Toxin
MY523_RS19550 4333852..4334103 - 252 WP_250656357.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
MY523_RS19555 4334589..4334855 + 267 WP_250656358.1 ribbon-helix-helix protein, CopG family -
MY523_RS19560 4334852..4335139 + 288 WP_250656359.1 type II toxin-antitoxin system RelE/ParE family toxin -
MY523_RS19565 4335217..4335474 + 258 WP_250656360.1 hypothetical protein -
MY523_RS19570 4335539..4335679 + 141 WP_250656361.1 hypothetical protein -
MY523_RS19575 4335865..4336593 - 729 WP_250658854.1 amino acid ABC transporter ATP-binding protein -
MY523_RS19580 4336648..4337754 - 1107 WP_250656362.1 amino acid ABC transporter permease -
MY523_RS19585 4337765..4338976 - 1212 WP_250656363.1 ABC transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10246.82 Da        Isoelectric Point: 10.0297

>T242696 WP_250656356.1 NZ_CP096016:c4333855-4333598 [Alkalimarinus coralli]
MKVTFSSAAWDQYLYWQTTDKKILKRINQLIKDIKREPYEGIGKPEPLKHGLAGYWSRRINDEHRIVYKYTEGTILIAQL
RYHYT

Download         Length: 258 bp

>T242696 NZ_OW849470:83870-84445 [Klebsiella oxytoca]
ATGCGACATTCACCTTATCCGGTGATTTTAGATGCCTGTGTGTTATATCCGGCACGACTCAGAGATTTGCTGATGCACCT
GGGGATTGCCGGGCTGTATCAACCAAAATGGAGCCGCTGCATTCAGGATGAATGGTGCAGAAACTTGATTGCTAATCGGC
CTGACATTCTGCCAGAGACGCTTCAGCGTACTGTCAAAATGATGAATTCCGCCTTACCAGATGCCAATGTTACGGGATAT
AAGGGATTAATAAGTAATCTGCATCTGCCGGATCCCAACGACAGACATGTTCTTGCCGCAGCGATAAGAGCGAAAGCTGA
AATTATTGTAACGCTTAACCATAAGAACTTTCCGCCAGAACTTCTGGGTCCATATGAAATAGAAACGCTTCACCCTGATG
CGTTTATTTCCGATCTCTTCGATCTTAATCATGCTCTGACGCTTGAAGCCGTCAGGCGGCAGCGACTGTCTCTAAAACAT
CCATCTATGGCGGTCGATGAATTTCTTGAAATGCTGCTAAAGCAGGGTTTACCGATGACGGTAAAGGAATTAGCGCATTA
TCAGTATGCTATTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9316.54 Da        Isoelectric Point: 4.4737

>AT242696 WP_250656357.1 NZ_CP096016:c4334103-4333852 [Alkalimarinus coralli]
MDAISYTHARANLSSTMEKVCNDHAPIIITRKSESPVVMMSLEDYQAMEETTYLLRSPANARQLLESIAELESGKGTERE
LLE

Download         Length: 252 bp

>AT242696 NZ_OW849470:83415-83870 [Klebsiella oxytoca]
ATGACTACACTGACTCATCTCAACCTTCCCGATCGCCAGGAGAGCGAACTTGCGCAGCGCGGACAGCGTGAGCTTGCGGC
GTATCTTTCCACCAGGCTGGAAACACAGCGTATTGCCATTGTAGGAGAGGATGATAAAGCTCATACCATAGAGCTACCTA
CAAGTGCGCTGACATTGCTGATGGAGATATTGGGGGAGTTGGCTAGCGGAAATGCGGTACAAATCGTTCCCGTACATGCG
GAACTCACAACCCAGGAGGCGGCAAATATACTCAATGTCTCTCGTCCGCATATGGTTAAGCTCCTGGAAGCGAGGAAGCT
CCCATTTCATAAAACGGGGCGTCATCGCAGAGTGTTGTTTGCCGATCTTATGGAGTATAAGAAACGCAGGGAACAGGAGA
GCCTGGACGCGATGCAATCATTGGCCGATCAGGCGCAGGACTTAGGGATGTATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References