Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4185684..4186209 Replicon chromosome
Accession NZ_CP096016
Organism Alkalimarinus coralli strain SCSIO 12582

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MY523_RS18775 Protein ID WP_250656208.1
Coordinates 4185925..4186209 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MY523_RS18770 Protein ID WP_250656207.1
Coordinates 4185684..4185935 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MY523_RS18740 4181210..4182118 - 909 WP_250656201.1 LysR family transcriptional regulator -
MY523_RS18745 4182287..4183006 + 720 WP_250656202.1 glutathione S-transferase family protein -
MY523_RS18750 4183226..4183891 + 666 WP_250656203.1 SDR family oxidoreductase -
MY523_RS18755 4183983..4184237 + 255 WP_250656204.1 hypothetical protein -
MY523_RS18760 4184271..4184924 - 654 WP_250656205.1 CBS domain-containing protein -
MY523_RS18765 4185091..4185456 - 366 WP_250656206.1 YbaN family protein -
MY523_RS18770 4185684..4185935 + 252 WP_250656207.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MY523_RS18775 4185925..4186209 + 285 WP_250656208.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MY523_RS18780 4186297..4187829 - 1533 WP_250656209.1 methyl-accepting chemotaxis protein -
MY523_RS18785 4188025..4188519 + 495 WP_250656210.1 peptidylprolyl isomerase -
MY523_RS18790 4188735..4189142 + 408 WP_250656211.1 GFA family protein -
MY523_RS18795 4189228..4190256 + 1029 WP_250656212.1 DUF2157 domain-containing protein -
MY523_RS18800 4190331..4190993 + 663 WP_250656213.1 YoaK family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(11-77)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10847.91 Da        Isoelectric Point: 10.7024

>T242695 WP_250656208.1 NZ_CP096016:4185925-4186209 [Alkalimarinus coralli]
MTYKLKFLPAALKEWKKLASPIQSQFKKKLSERLENPRVPSAKLSGFDSVYKIKLRTAGYRLAYEVVDDEVVVYVLVVGK
RDKGKVYQKLKGRI

Download         Length: 285 bp

>T242695 NZ_OW849378:89057-89455 [Escherichia coli]
ATGCTGAAGTTTATGCTCGATACCAACATCTGCATTTTCACGATAAAGAACAAACCCGCCAGCGTCAGGGAGCGTTTTAA
CCTGAACCAGGGGAGAATGTGTATCAGTTCGGTCACCCTGATGGAGCTGATATATGGTGCAGAAAAAAGCCAGATGCCTG
AACGTAATCTCGCTGTGATCGAGGGATTTGTTTCCCGCATTGATGTTCTGGATTACGACGCTGCCGCAGCCACACACAGC
GGCCAGATAAGAGCAGAACTTGCCCGTCAGGGACGCCCTGTCGGGCCATTTGATCAAATGATCGCAGGTCATGCCCGCAG
TCGGGGACTGATTATTGTGACTAATAACACCCGGGAATTTGAACGTGTGGACGGTCTGAGAATTGAAGACTGGAGCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9152.48 Da        Isoelectric Point: 4.2813

>AT242695 WP_250656207.1 NZ_CP096016:4185684-4185935 [Alkalimarinus coralli]
MRQVLADCSASISELKKNPTALLNESAGAPIAILNHNKPAAYLVPAETYEWLMDMLDDQELAKLVEQRVAKKDQAVEVSL
DDL

Download         Length: 252 bp

>AT242695 NZ_OW849378:88830-89057 [Escherichia coli]
ATGGAAACCACCGTATTTTTCAGCAACCGCAGCCAGGCGGTCAGACTGCCAAAAGCGGTTGCATTGCCGGAAAACGTAAA
ACGCGTTGAAGTGATTGCTGTCGGACGAACCAGAATCATTACGCCAGCCGGAGAGACATGGGACGAATGGTTCGACGGAC
ACAACGTCAGCGCCGATTTTATGGATAACAGGGAACAGCCCGGCATGCAGGAAAGGGAGTCATTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References