Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4185684..4186209 Replicon chromosome
Accession NZ_CP096016
Organism Alkalimarinus coralli strain SCSIO 12582

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MY523_RS18775 Protein ID WP_250656208.1
Coordinates 4185925..4186209 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MY523_RS18770 Protein ID WP_250656207.1
Coordinates 4185684..4185935 (+) Length 84 a.a.

Genomic Context

MY523_RS18745MY523_RS18750MY523_RS18755MY523_RS18770MY523_RS18775MY523_RS18785MY523_RS18790MY523_RS18795MY523_RS18800MY523_RS18740MY523_RS18760MY523_RS18765MY523_RS18780
Location: 4182287..4183006 (720 bp)
Type: Others
Protein ID: WP_250656202.1
Location: 4183226..4183891 (666 bp)
Type: Others
Protein ID: WP_250656203.1
Location: 4183983..4184237 (255 bp)
Type: Others
Protein ID: WP_250656204.1
Location: 4185684..4185935 (252 bp)
Type: Antitoxin
Protein ID: WP_250656207.1
Location: 4185925..4186209 (285 bp)
Type: Toxin
Protein ID: WP_250656208.1
Location: 4188025..4188519 (495 bp)
Type: Others
Protein ID: WP_250656210.1
Location: 4188735..4189142 (408 bp)
Type: Others
Protein ID: WP_250656211.1
Location: 4189228..4190256 (1029 bp)
Type: Others
Protein ID: WP_250656212.1
Location: 4190331..4190993 (663 bp)
Type: Others
Protein ID: WP_250656213.1
Location: 4181210..4182118 (909 bp)
Type: Others
Protein ID: WP_250656201.1
Location: 4184271..4184924 (654 bp)
Type: Others
Protein ID: WP_250656205.1
Location: 4185091..4185456 (366 bp)
Type: Others
Protein ID: WP_250656206.1
Location: 4186297..4187829 (1533 bp)
Type: Others
Protein ID: WP_250656209.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MY523_RS187404181210..4182118-909WP_250656201.1LysR family transcriptional regulator-
MY523_RS187454182287..4183006+720WP_250656202.1glutathione S-transferase family protein-
MY523_RS187504183226..4183891+666WP_250656203.1SDR family oxidoreductase-
MY523_RS187554183983..4184237+255WP_250656204.1hypothetical protein-
MY523_RS187604184271..4184924-654WP_250656205.1CBS domain-containing protein-
MY523_RS187654185091..4185456-366WP_250656206.1YbaN family protein-
MY523_RS187704185684..4185935+252WP_250656207.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
MY523_RS187754185925..4186209+285WP_250656208.1type II toxin-antitoxin system RelE/ParE family toxinToxin
MY523_RS187804186297..4187829-1533WP_250656209.1methyl-accepting chemotaxis protein-
MY523_RS187854188025..4188519+495WP_250656210.1peptidylprolyl isomerase-
MY523_RS187904188735..4189142+408WP_250656211.1GFA family protein-
MY523_RS187954189228..4190256+1029WP_250656212.1DUF2157 domain-containing protein-
MY523_RS188004190331..4190993+663WP_250656213.1YoaK family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(11-77)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10847.91 Da        Isoelectric Point: 10.7024

>T242695 WP_250656208.1 NZ_CP096016:4185925-4186209 [Alkalimarinus coralli]
MTYKLKFLPAALKEWKKLASPIQSQFKKKLSERLENPRVPSAKLSGFDSVYKIKLRTAGYRLAYEVVDDEVVVYVLVVGK
RDKGKVYQKLKGRI

Download         Length: 285 bp

>T242695 NZ_OW849378:89057-89455 [Escherichia coli]
ATGCTGAAGTTTATGCTCGATACCAACATCTGCATTTTCACGATAAAGAACAAACCCGCCAGCGTCAGGGAGCGTTTTAA
CCTGAACCAGGGGAGAATGTGTATCAGTTCGGTCACCCTGATGGAGCTGATATATGGTGCAGAAAAAAGCCAGATGCCTG
AACGTAATCTCGCTGTGATCGAGGGATTTGTTTCCCGCATTGATGTTCTGGATTACGACGCTGCCGCAGCCACACACAGC
GGCCAGATAAGAGCAGAACTTGCCCGTCAGGGACGCCCTGTCGGGCCATTTGATCAAATGATCGCAGGTCATGCCCGCAG
TCGGGGACTGATTATTGTGACTAATAACACCCGGGAATTTGAACGTGTGGACGGTCTGAGAATTGAAGACTGGAGCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9152.48 Da        Isoelectric Point: 4.2813

>AT242695 WP_250656207.1 NZ_CP096016:4185684-4185935 [Alkalimarinus coralli]
MRQVLADCSASISELKKNPTALLNESAGAPIAILNHNKPAAYLVPAETYEWLMDMLDDQELAKLVEQRVAKKDQAVEVSL
DDL

Download         Length: 252 bp

>AT242695 NZ_OW849378:88830-89057 [Escherichia coli]
ATGGAAACCACCGTATTTTTCAGCAACCGCAGCCAGGCGGTCAGACTGCCAAAAGCGGTTGCATTGCCGGAAAACGTAAA
ACGCGTTGAAGTGATTGCTGTCGGACGAACCAGAATCATTACGCCAGCCGGAGAGACATGGGACGAATGGTTCGACGGAC
ACAACGTCAGCGCCGATTTTATGGATAACAGGGAACAGCCCGGCATGCAGGAAAGGGAGTCATTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References