Detailed information of TA system TA242693

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-RHH
• Location: 2993847..2994409
• Replicon: chromosome
• Accession: NZ_CP096016
• Organism: Alkalimarinus coralli strain SCSIO 12582

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: MY523_RS13425
• Protein ID: WP_250655205.1
• Coordinates: 2994095..2994409 (+)
• Length: 105 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: MY523_RS13420
• Protein ID: WP_250655204.1
• Coordinates: 2993847..2994095 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (9-96)

Antitoxin

• Antitoxin ParD (1-79)

Sequences

Toxin

Protein

• Length: 105 a.a.
• Molecular weight: 12339.05 Da
• Isoelectric Point: 9.6406

>T242693 WP_250655205.1 NZ_CP096016:2994095-2994409 [Alkalimarinus coralli]
VKQKINSKVRVTPRARDDLKNIGRYTEQTWGKTQRNRYLKSIDARFHWLAENPQLGKHRTDICEEYYSFPEGQHVVFYLI
GRNSIDIIGIPHKEMDIISYFLEG

Nucleotide

• Length: 315 bp

>T242693 NZ_OW849377:c4610403-4610092 [Escherichia coli]
ATGCTCTTCATCGAAACGGAAATTTTTACTGAAGATGTTCAAAAACTGCTGACCGACGATGAATTCAGTCGTTTTCAGTT
TTTCCTGGCCTTGAATCCTGACTATGGTGAGGTAATACCTGAAACTGGTGGGTTAAGAAAGGTTCGATGGGTTTCAGGAG
GAAAGGGGAAACGTGCTGGTGTCAGGGTTATTTACTTTCATCAGGTTAAACATTATGAGATCAGATTACTGCTTATTTAT
CGTAAGGGTATTAAAGATGATCTGTCTCCCCAGGAAAAAGCAATGCTCCGGTTGTTAAATACGAGGTGGTAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9007.90 Da
• Isoelectric Point: 4.3431

>AT242693 WP_250655204.1 NZ_CP096016:2993847-2994095 [Alkalimarinus coralli]
MATTSLSLGEHWEVFIKNEISSGRYGSASEVVRDALRAMEERKSKLEALRSHLAEGATQASNGDFVDNFSMDSLINDLDA
ET

Nucleotide

• Length: 249 bp

>AT242693 NZ_OW849377:c4610091-4609801 [Escherichia coli]
ATGGATAAGGCACTTTTTGAGCGGTTGACTCACAGCATGGCCCAGATGAATGAAATTATTGAAGGAACGCGACAGCCTTC
GCGGACTTTTGAAGTTGATGCTATGAAAATCAAAGAAATACGCCGCGCTTCAGGGTTGTCACAATCTAAATTTGCCGATC
TTATTTCTGTAAGCGTAGACACGTTGCGTAACTGGGAGCAGGGGCGACGTTCACCGACCGGGCCTGCAAAGGCTTTGCTG
CGAGCGATTGCCAATGATCCGCAACATGTGCTGCAAGCACTTAACCGTTAG