Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 2993847..2994409 Replicon chromosome
Accession NZ_CP096016
Organism Alkalimarinus coralli strain SCSIO 12582

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag MY523_RS13425 Protein ID WP_250655205.1
Coordinates 2994095..2994409 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag MY523_RS13420 Protein ID WP_250655204.1
Coordinates 2993847..2994095 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MY523_RS13390 2991435..2991650 - 216 WP_045857757.1 helix-turn-helix domain-containing protein -
MY523_RS13395 2991910..2992158 - 249 WP_250655199.1 helix-turn-helix domain-containing protein -
MY523_RS13400 2992239..2992541 + 303 WP_250655200.1 type II toxin-antitoxin system HigB family toxin -
MY523_RS13405 2992634..2993002 + 369 WP_250655201.1 transcriptional regulator -
MY523_RS13410 2992995..2993327 + 333 WP_250655202.1 hypothetical protein -
MY523_RS13415 2993387..2993701 + 315 WP_250655203.1 hypothetical protein -
MY523_RS13420 2993847..2994095 + 249 WP_250655204.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
MY523_RS13425 2994095..2994409 + 315 WP_250655205.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MY523_RS13430 2994606..2994788 - 183 WP_250655206.1 hypothetical protein -
MY523_RS13435 2994788..2995063 - 276 WP_250655207.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
MY523_RS13440 2995264..2995728 - 465 WP_250655208.1 M15 family metallopeptidase -
MY523_RS13445 2996120..2996827 + 708 WP_250655209.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-96)

Antitoxin

Antitoxin ParD

(1-79)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 12339.05 Da        Isoelectric Point: 9.6406

>T242693 WP_250655205.1 NZ_CP096016:2994095-2994409 [Alkalimarinus coralli]
VKQKINSKVRVTPRARDDLKNIGRYTEQTWGKTQRNRYLKSIDARFHWLAENPQLGKHRTDICEEYYSFPEGQHVVFYLI
GRNSIDIIGIPHKEMDIISYFLEG

Download         Length: 315 bp

>T242693 NZ_OW849377:c4610403-4610092 [Escherichia coli]
ATGCTCTTCATCGAAACGGAAATTTTTACTGAAGATGTTCAAAAACTGCTGACCGACGATGAATTCAGTCGTTTTCAGTT
TTTCCTGGCCTTGAATCCTGACTATGGTGAGGTAATACCTGAAACTGGTGGGTTAAGAAAGGTTCGATGGGTTTCAGGAG
GAAAGGGGAAACGTGCTGGTGTCAGGGTTATTTACTTTCATCAGGTTAAACATTATGAGATCAGATTACTGCTTATTTAT
CGTAAGGGTATTAAAGATGATCTGTCTCCCCAGGAAAAAGCAATGCTCCGGTTGTTAAATACGAGGTGGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9007.90 Da        Isoelectric Point: 4.3431

>AT242693 WP_250655204.1 NZ_CP096016:2993847-2994095 [Alkalimarinus coralli]
MATTSLSLGEHWEVFIKNEISSGRYGSASEVVRDALRAMEERKSKLEALRSHLAEGATQASNGDFVDNFSMDSLINDLDA
ET

Download         Length: 249 bp

>AT242693 NZ_OW849377:c4610091-4609801 [Escherichia coli]
ATGGATAAGGCACTTTTTGAGCGGTTGACTCACAGCATGGCCCAGATGAATGAAATTATTGAAGGAACGCGACAGCCTTC
GCGGACTTTTGAAGTTGATGCTATGAAAATCAAAGAAATACGCCGCGCTTCAGGGTTGTCACAATCTAAATTTGCCGATC
TTATTTCTGTAAGCGTAGACACGTTGCGTAACTGGGAGCAGGGGCGACGTTCACCGACCGGGCCTGCAAAGGCTTTGCTG
CGAGCGATTGCCAATGATCCGCAACATGTGCTGCAAGCACTTAACCGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References