Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 2615632..2616136 Replicon chromosome
Accession NZ_CP096016
Organism Alkalimarinus coralli strain SCSIO 12582

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag MY523_RS11580 Protein ID WP_250654860.1
Coordinates 2615873..2616136 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag MY523_RS11575 Protein ID WP_250654859.1
Coordinates 2615632..2615883 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MY523_RS11545 2610734..2611753 + 1020 WP_250654853.1 PhoH family protein -
MY523_RS11550 2611750..2612232 + 483 WP_250654854.1 rRNA maturation RNase YbeY -
MY523_RS11555 2612229..2613071 + 843 WP_250654855.1 transporter associated domain-containing protein -
MY523_RS11560 2613170..2614798 + 1629 WP_250654856.1 apolipoprotein N-acyltransferase -
MY523_RS11565 2614994..2615305 - 312 WP_250654857.1 type II toxin-antitoxin system RelE/ParE family toxin -
MY523_RS11570 2615293..2615550 - 258 WP_250654858.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
MY523_RS11575 2615632..2615883 - 252 WP_250654859.1 CopG family transcriptional regulator Antitoxin
MY523_RS11580 2615873..2616136 - 264 WP_250654860.1 BrnT family toxin Toxin
MY523_RS11585 2616682..2616918 + 237 WP_250654861.1 addiction module protein -
MY523_RS11590 2616923..2617234 + 312 WP_250654862.1 type II toxin-antitoxin system RelE/ParE family toxin -
MY523_RS11595 2617495..2617797 - 303 WP_250654863.1 hypothetical protein -
MY523_RS11600 2617794..2618072 - 279 WP_250654864.1 BrnT family toxin -
MY523_RS11605 2618663..2619133 - 471 WP_250654865.1 GNAT family N-acetyltransferase -
MY523_RS11610 2619231..2620562 - 1332 WP_250654866.1 group II intron reverse transcriptase/maturase -
MY523_RS11615 2620598..2620762 - 165 WP_250654867.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integron - - 2613170..2617797 4627


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-81)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10120.37 Da        Isoelectric Point: 6.7196

>T242692 WP_250654860.1 NZ_CP096016:c2616136-2615873 [Alkalimarinus coralli]
MYNFEFDHKKSNSNLDKHGIDFNEAQSLWGDPDLIEIQAKSEDEPRSLVIGRIGEKHWSAVITCRKESIRIISVRRSRKT
EVALYES

Download         Length: 264 bp

>T242692 NZ_OW849377:c4288918-4288745 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9698.01 Da        Isoelectric Point: 8.6572

>AT242692 WP_250654859.1 NZ_CP096016:c2615883-2615632 [Alkalimarinus coralli]
MKAKDFDKKFDNNEDIIDDLDLSSIKRPNQAQKRVNVDFPTWMIDSLDKEANRVGVTRQSIIKVWLAEKLEEQAANKALH
RTR

Download         Length: 252 bp

>AT242692 NZ_OW849377:c4289242-4288946 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAATTTCTCTTCTATCGTGGCTGATGAATATGGGATACCACGACAATTGAATGAAAATT
CTTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GATTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References