Detailed information of TA system TA242691

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 2614994..2615550
• Replicon: chromosome
• Accession: NZ_CP096016
• Organism: Alkalimarinus coralli strain SCSIO 12582

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: MY523_RS11565
• Protein ID: WP_250654857.1
• Coordinates: 2614994..2615305 (-)
• Length: 104 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: MY523_RS11570
• Protein ID: WP_250654858.1
• Coordinates: 2615293..2615550 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integron	-	-	2613170..2617797	4627

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-70)

Sequences

Toxin

Protein

• Length: 104 a.a.
• Molecular weight: 11937.56 Da
• Isoelectric Point: 4.5858

>T242691 WP_250654857.1 NZ_CP096016:c2615305-2614994 [Alkalimarinus coralli]
MAQIIWTEPALNDLNDIAEYIAVSNPYAAKQLVENVFSNVQRLEQFPDSGRVPDEISNLNYREVVVNPCRVFYKIDMDSV
YILHVMRQERDLRKFLLSTTNGS

Nucleotide

• Length: 312 bp

>T242691 NZ_OW849377:c4191302-4190952 [Escherichia coli]
ATGGTAAAGAAAAGTGAATTTGAACGGGGAGACATTGTGCTGGTTGGCTTTGATCCAGCAAGCGGCCATGAACAGCAAGG
TGCTGGTCGACCTGCGCTTGTGCTCTCCGTTCAAGCCTTTAATCAACTGGGAATGACGCTGGTGGCCCCCATTACGCAGG
GCGGAAATTTTGCCCGTTATGCCGGATTTAGCGTTCCTTTACATTGCGAAGAAGGCGATGTGCACGGCGTGGTGCTGGTG
AATCAGGTGCGGATGATGGATCTACGCGCCCGGCTGGCAAAGCGTATTGGTCTGGCTGCGGATGAGGTGGTGGAAGAGGC
GTTATTACGCTTGCAGGCGGTGGTGGAATAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9713.35 Da
• Isoelectric Point: 8.5371

>AT242691 WP_250654858.1 NZ_CP096016:c2615550-2615293 [Alkalimarinus coralli]
MRTEVVTTLKRQATKLLADLHESKEPILITEHGQPSAYLLDVADYELMVNRMKILEGIAKGEQAIRDGRTMDMGQAKDKM
NKWLK

Nucleotide

• Length: 258 bp

>AT242691 NZ_OW849377:c4191547-4191296 [Escherichia coli]
ATGCGTATTACCATAAAAAGATGGGGGAACAGTGCAGGTATGGTCATTCCCAATATCTTAATGAAAGAACTTAACTTACA
GCCGGGGCAGAGCGTGGAAGCGCAGGTGAGCAACAACCAACTGATTCTGACACCCATCTCCAGGCGCTACTCGCTTGATG
AACTGCTGGCACAGTGTGACATGAACGCCGCGGAACTTAGCGAGCAGGATGTCTGGGGTAAATCCACCCCTGCGGGTGAC
GAAATATGGTAA