Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1598949..1599515 Replicon chromosome
Accession NZ_CP096016
Organism Alkalimarinus coralli strain SCSIO 12582

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MY523_RS07100 Protein ID WP_250658091.1
Coordinates 1598949..1599233 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MY523_RS07105 Protein ID WP_250658092.1
Coordinates 1599237..1599515 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MY523_RS07070 1594665..1594895 + 231 WP_250658085.1 hypothetical protein -
MY523_RS07075 1594895..1595287 + 393 WP_250658086.1 type II toxin-antitoxin system VapC family toxin -
MY523_RS07080 1595577..1596125 + 549 WP_250658087.1 hypothetical protein -
MY523_RS07090 1597490..1597909 + 420 WP_250658089.1 hypothetical protein -
MY523_RS07095 1598249..1598731 + 483 WP_250658090.1 hypothetical protein -
MY523_RS07100 1598949..1599233 - 285 WP_250658091.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MY523_RS07105 1599237..1599515 - 279 WP_250658092.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MY523_RS07110 1599856..1600359 + 504 WP_250658093.1 hypothetical protein -
MY523_RS07115 1600426..1600797 + 372 WP_250658094.1 helix-turn-helix domain-containing protein -
MY523_RS07120 1601008..1601964 - 957 WP_250658095.1 PA2778 family cysteine peptidase -
MY523_RS07125 1602018..1602422 - 405 WP_250658096.1 PA2779 family protein -
MY523_RS07130 1602737..1604185 - 1449 WP_250658097.1 aldehyde dehydrogenase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-44)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11183.95 Da        Isoelectric Point: 6.4718

>T242689 WP_250658091.1 NZ_CP096016:c1599233-1598949 [Alkalimarinus coralli]
VIYWEEESLNDRERIFEFLYDFNPIAAEKTDKIIEEKVENLHQQPLMGVQRGGIQGRLLVIPEISMIVSYWTDNTVIRVM
RVLHQKQKFPAKRP

Download         Length: 285 bp

>T242689 NZ_OW849377:3725993-3726271 [Escherichia coli]
ATGATTCAAAGGGATATTGAATACTCGGGACAATTTTCAAAGGATGTAAAACTTGCACAAAAGCGTCATAAGGATATGAA
TAAATTGAAATATCTTATGACGCTTCTTATCAATAATGCTTTACCGCTTCCAGCTGTTTATAAAGACCACCCGCTGCAAG
GTTCATGGAAAGGTTATCGCGATGCTCATGTCGAACCGGACTGGATCCTGATTTACAAACTTACCGATAAACTTTTACGA
TTTGAGAGAACTGGAACTCACGCGGCGCTCTTTGGGTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10885.07 Da        Isoelectric Point: 7.8949

>AT242689 WP_250658092.1 NZ_CP096016:c1599515-1599237 [Alkalimarinus coralli]
MDTRVQFRIDEETKRLAQQRTESQGRTLSDACRELTEQLADQQRKATSHDAWLTEQVNLAFEKFQTNRSTFVEHEHAKSS
MSERKAKIRERC

Download         Length: 279 bp

>AT242689 NZ_OW849377:3725730-3725990 [Escherichia coli]
ATGGCTGCTAACGCATTTGTTCGCGCCCGAATCGATGAAGATCTGAAGAATCAGGCGGCGGACGTACTGGCCGGGATGGG
GCTGACCATCTCTGACCTGGTTCGCATAACCCTCACAAAGGTCGCGCGTGAAAAGGCATTGCCGTTTGATTTACGCGAGC
CTAATCAATTAACCATTCAATCAATCAAAAACAGCGAAGCTGGCGTTGATGTTCATAAGGCCAAAGACGCCGATGATTTA
TTTGATAAATTAGGAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References