Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 912697..913207 Replicon chromosome
Accession NZ_CP096016
Organism Alkalimarinus coralli strain SCSIO 12582

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag MY523_RS04025 Protein ID WP_250657524.1
Coordinates 912944..913207 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag MY523_RS04020 Protein ID WP_250657523.1
Coordinates 912697..912951 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MY523_RS03995 908571..909215 + 645 WP_250657518.1 DUF5610 domain-containing protein -
MY523_RS04000 909330..910001 + 672 WP_250657519.1 hypothetical protein -
MY523_RS04005 910141..910542 + 402 WP_250657520.1 DUF4345 family protein -
MY523_RS04010 910591..911256 - 666 WP_250657521.1 Frag1/DRAM/Sfk1 family protein -
MY523_RS04015 911504..912139 + 636 WP_250657522.1 glutathione S-transferase family protein -
MY523_RS04020 912697..912951 + 255 WP_250657523.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
MY523_RS04025 912944..913207 + 264 WP_250657524.1 Txe/YoeB family addiction module toxin Toxin
MY523_RS04030 913782..914255 + 474 WP_250657525.1 GNAT family N-acetyltransferase -
MY523_RS04035 914278..914796 + 519 WP_250657526.1 GNAT family N-acetyltransferase -
MY523_RS04040 915011..915454 + 444 WP_250657527.1 hypothetical protein -
MY523_RS04045 915524..916162 + 639 WP_250657528.1 hypothetical protein -
MY523_RS04050 916273..916515 + 243 WP_250657529.1 DUF4282 domain-containing protein -
MY523_RS04055 916597..917004 + 408 WP_250657530.1 DUF4345 domain-containing protein -
MY523_RS04060 917150..917848 + 699 WP_250657531.1 TIGR02117 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10321.72 Da        Isoelectric Point: 9.3455

>T242687 WP_250657524.1 NZ_CP096016:912944-913207 [Alkalimarinus coralli]
MSSRLLVWTDEAWSDYLYWQGQDKKTLKRINKLISDSKRAPFEGIGKPEPLKEYLSGFWSRRIDDTNRLVYAVDNTSLTV
ISCRYHY

Download         Length: 264 bp

>T242687 NZ_OW849377:3516850-3517068 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTATACGACAAGATCCCTTCCTCAGTATGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9322.51 Da        Isoelectric Point: 5.0481

>AT242687 WP_250657523.1 NZ_CP096016:912697-912951 [Alkalimarinus coralli]
MKIVSFTEARNGLKAVLDSVVNDADSAIITRRDSEDAVVMSLNYYNSLMETVHLLRSPANAEHLAKSIDQFRKGSATPRD
LIDE

Download         Length: 255 bp

>AT242687 NZ_OW849377:3516450-3516824 [Escherichia coli]
ATGGATGAATACTCACCCAAAAGACATGATATCGCACAGCTTAAGTTTCTCTGTGAAACCCTGTATCATGACTGCCTTGC
AAACCTTGAAGAAAGCAATCATGGCTGGGTTAACGACCCAACCTCGGCGATCAACCTCCAGTTGAATGAACTGATTGAGC
ATATTGCGACCTTCGCACTTAATTACAAAATTAAGTATAATGAAGACAATAAGCTCATTGAGCAGATCGACGAATATCTG
GATGACACCTTTATGTTGTTCAGTAGTTATGGTATTAATATGCAGGATCTTCAGAAATGGCGGAAGTCAGGTAATCGACT
ATTCCGTTGTTTTGTCAATGCGACGAAAGAGAATCCTGCGAGTTTATCTTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References