Detailed information of TA system TA242679

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PanAT/DUF4065(antitoxin)
• Location: 295152..296107
• Replicon: chromosome
• Accession: NZ_CP095923
• Organism: Pseudomonas aeruginosa strain AR19438

Toxin (Protein)

• Gene name: panT
• Uniprot ID: -
• Locus tag: MX621_RS01350
• Protein ID: WP_170868726.1
• Coordinates: 295781..296107 (+)
• Length: 109 a.a.

Antitoxin (Protein)

• Gene name: panA
• Uniprot ID: -
• Locus tag: MX621_RS01345
• Protein ID: WP_023107584.1
• Coordinates: 295152..295709 (+)
• Length: 186 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MX621_RS01320 (MX621_01320)	290209..290496	-	288	WP_023443569.1	hypothetical protein	-
MX621_RS01325 (MX621_01325)	290588..291064	-	477	WP_009315008.1	MarR family transcriptional regulator	-
MX621_RS01330 (MX621_01330)	291105..292595	-	1491	WP_003111463.1	UbiD family decarboxylase HudA	-
MX621_RS01335 (MX621_01335)	292729..293415	-	687	WP_003106170.1	YoaK family protein	-
MX621_RS01340 (MX621_01340)	293579..294511	-	933	WP_023108709.1	hypothetical protein	-
MX621_RS01345 (MX621_01345)	295152..295709	+	558	WP_023107584.1	Panacea domain-containing protein	Antitoxin
MX621_RS01350 (MX621_01350)	295781..296107	+	327	WP_170868726.1	hypothetical protein	Toxin
MX621_RS01360 (MX621_01360)	297552..299144	-	1593	WP_277424738.1	DUF2875 family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Antitoxin SocA-like, Panacea domain (28-138)

Sequences

Toxin

Protein

• Length: 109 a.a.
• Molecular weight: 12366.33 Da
• Isoelectric Point: 8.6957

>T242679 WP_170868726.1 NZ_CP095923:295781-296107 [Pseudomonas aeruginosa]
MNDPVYCPVLGYDAVLLVNISTVYPDKYFDQSCILKKGCHPFVLHDSWVVYREAGPFNLARLEQGVAQKSIKTHQPINAG
DFTRIRAGFDISPDVKIKVERFMRQHKI

Nucleotide

• Length: 327 bp

>T242679 NZ_OW849377:901581-901988 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCTGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin

Protein

• Length: 186 a.a.
• Molecular weight: 21377.14 Da
• Isoelectric Point: 5.8950

>AT242679 WP_023107584.1 NZ_CP095923:295152-295709 [Pseudomonas aeruginosa]
VIFSEQKVAHMAAFFLASAEGPLPHLTLIKLLYLADRESMARFDVPMSDDRAVSMPHGPVLSSTLDLIKGRLRSEVWSAW
ISPLVDHEVRLVHDVENWDDLDELSRSDRSILESVWQEFGHMTKYQLRDYTHHHIGEWHDPHGSSRDIDPKDTFMALGQS
EELAEIKARDLAERRRHGRKLSEFI

Nucleotide

• Length: 558 bp

>AT242679 NZ_OW849377:901334-901600 [Escherichia coli]
ATGGACATTAATAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA