Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 4088532..4089091 Replicon chromosome
Accession NZ_CP095851
Organism Rhodococcus pyridinivorans strain YC-MTN

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MYP14_RS19295 Protein ID WP_080678595.1
Coordinates 4088846..4089091 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MYP14_RS19290 Protein ID WP_024102980.1
Coordinates 4088532..4088816 (+) Length 95 a.a.

Genomic Context

MYP14_RS19265MYP14_RS19270MYP14_RS19275MYP14_RS19280MYP14_RS19285MYP14_RS19290MYP14_RS19295MYP14_RS19315MYP14_RS19320MYP14_RS19300MYP14_RS19305MYP14_RS19310MYP14_RS19325
Location: 4083735..4084361 (627 bp)
Type: Others
Protein ID: WP_231913210.1
Location: 4084358..4084786 (429 bp)
Type: Others
Protein ID: WP_024102975.1
Location: 4084791..4086392 (1602 bp)
Type: Others
Protein ID: WP_039585873.1
Location: 4086469..4087497 (1029 bp)
Type: Others
Protein ID: WP_033096849.1
Location: 4087494..4088312 (819 bp)
Type: Others
Protein ID: WP_247848529.1
Location: 4088532..4088816 (285 bp)
Type: Antitoxin
Protein ID: WP_024102980.1
Location: 4088846..4089091 (246 bp)
Type: Toxin
Protein ID: WP_080678595.1
Location: 4091368..4092198 (831 bp)
Type: Others
Protein ID: WP_006551851.1
Location: 4092243..4093214 (972 bp)
Type: Others
Protein ID: WP_006551850.1
Location: 4089148..4089627 (480 bp)
Type: Others
Protein ID: WP_006551854.1
Location: 4089686..4090435 (750 bp)
Type: Others
Protein ID: WP_024102983.1
Location: 4090585..4091247 (663 bp)
Type: Others
Protein ID: WP_033096847.1
Location: 4093251..4093970 (720 bp)
Type: Others
Protein ID: WP_247848530.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MYP14_RS19265 (MYP14_19265)4083735..4084361+627WP_231913210.1TetR/AcrR family transcriptional regulator-
MYP14_RS19270 (MYP14_19270)4084358..4084786+429WP_024102975.1HIT family protein-
MYP14_RS19275 (MYP14_19275)4084791..4086392+1602WP_039585873.1L-lactate permease-
MYP14_RS19280 (MYP14_19280)4086469..4087497+1029WP_033096849.1Dyp-type peroxidase-
MYP14_RS19285 (MYP14_19285)4087494..4088312+819WP_247848529.1family 1 encapsulin nanocompartment shell protein-
MYP14_RS19290 (MYP14_19290)4088532..4088816+285WP_024102980.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
MYP14_RS19295 (MYP14_19295)4088846..4089091+246WP_080678595.1type II toxin-antitoxin system RelE/ParE family toxinToxin
MYP14_RS19300 (MYP14_19300)4089148..4089627-480WP_006551854.1MarR family transcriptional regulator-
MYP14_RS19305 (MYP14_19305)4089686..4090435-750WP_024102983.1cutinase family protein-
MYP14_RS19310 (MYP14_19310)4090585..4091247-663WP_033096847.1alpha-ketoglutarate-dependent dioxygenase AlkB-
MYP14_RS19315 (MYP14_19315)4091368..4092198+831WP_006551851.1SDR family oxidoreductase-
MYP14_RS19320 (MYP14_19320)4092243..4093214+972WP_006551850.1phosphotriesterase-
MYP14_RS19325 (MYP14_19325)4093251..4093970-720WP_247848530.12OG-Fe(II) oxygenase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(29-80)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 8971.32 Da        Isoelectric Point: 10.3368

>T242624 WP_080678595.1 NZ_CP095851:4088846-4089091 [Rhodococcus pyridinivorans]
MARSAARAMARSLPEKVATAVYEFVTGPLLENPKRVGKPLNPPLAPAYSARRGEYRVLYLIDDANRTVEVTAISHRADAY
R

Download         Length: 246 bp

>T242624 NZ_OW849064:3494392-3494703 [Escherichia coli]
ATGCTCTTCATCGAAACGGAAATTTTTACTGAAGATGTTCAAAAACTGCTGAACGACGATGAATTCAGTCGTTTTCAGTT
TTTCCTGGCCTTGAATCCTGACTATGGTGAGGTAATACCTGAAACTGGTGGGTTAAGAAAGGTTCGATGGGTCTCAGGAG
GAAAGGGGAAACGTGCTGGTGTCAGGGTTATTTACTTTCATCAGGTTAAACATTATGAGATCAGATTACTGCTTATTTAT
CGTAAGGGTATTAAAGATGATCTGTCTCCCCAGGAAAAAGCAATGCTCCGGTTGTTAAATACGAGGTGGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10494.56 Da        Isoelectric Point: 4.2336

>AT242624 WP_024102980.1 NZ_CP095851:4088532-4088816 [Rhodococcus pyridinivorans]
MTTLPVADARAQLSRLVDEAERTHERFEITRNGHRAAVLLGADDYDAMQETIAVLSDTDLLRAHVEGRTEVESGDVVDVQ
ELTQLMRDARSSEE

Download         Length: 285 bp

>AT242624 NZ_OW849064:3494704-3494994 [Escherichia coli]
ATGGATAAGGCACTTTTTGAGCGGTTGACTCACAGCATGGCCCAGATGAATGAAATTATTGAAGGAACGCGACAGCCTTC
ACGGACTTTTGAAGTTGATGCTATGAAAATCAAAGAAATACGCCGCGCTTCAGGGTTGTCACAATCTAAATTTGCCGATC
TTATTTCCGTAAGCGTAGACACGTTGCGTAACTGGGAGCAGGGGCGACGTTCACCGACCGGGCCTGCAAAGGCTTTGCTG
CGAGCGATTGCCAATGATCCGCAACATGTGCTGCAAGCACTTAACCGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References