Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pezAT/zeta-ParD
Location 839008..839960 Replicon chromosome
Accession NZ_CP095851
Organism Rhodococcus pyridinivorans strain YC-MTN

Toxin (Protein)


Gene name pezT Uniprot ID H0JT30
Locus tag MYP14_RS03920 Protein ID WP_006552790.1
Coordinates 839008..839577 (-) Length 190 a.a.

Antitoxin (Protein)


Gene name pezA Uniprot ID H0JT29
Locus tag MYP14_RS03925 Protein ID WP_006552789.1
Coordinates 839574..839960 (-) Length 129 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MYP14_RS03920 (MYP14_03920) 839008..839577 - 570 WP_006552790.1 zeta toxin family protein Toxin
MYP14_RS03925 (MYP14_03925) 839574..839960 - 387 WP_006552789.1 hypothetical protein Antitoxin
MYP14_RS03930 (MYP14_03930) 840167..841237 + 1071 WP_019289578.1 methyltransferase domain-containing protein -
MYP14_RS03935 (MYP14_03935) 841307..841672 + 366 WP_039585980.1 HNH endonuclease -
MYP14_RS03940 (MYP14_03940) 841689..842189 - 501 WP_247849119.1 hypothetical protein -
MYP14_RS03945 (MYP14_03945) 843309..844241 - 933 WP_039585976.1 TAXI family TRAP transporter solute-binding subunit -
MYP14_RS03950 (MYP14_03950) 844238..844957 - 720 WP_247849120.1 HAMP domain-containing sensor histidine kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Zeta toxin domain

(4-136)

Antitoxin

ParD-like antitoxin of type II bacterial toxin-antitoxin system

(7-79)


Sequences

Toxin        


Download         Length: 190 a.a.        Molecular weight: 20552.71 Da        Isoelectric Point: 10.6895

>T242623 WP_006552790.1 NZ_CP095851:c839577-839008 [Rhodococcus pyridinivorans]
MRRLDLIVGPNGSGKSTFVELSLAPLLPRSVFVNADVIARQRWPDRAEEMSYEAAQLAAAARDRLLRQGRSFIAETVFSH
PSKLELIDRAHEVGFTVVLHVMLVPEAMSVLRVQHRVASGGHAVPEDKIRARYRRLWPLVTEAIGRADQASVYDTASGTP
VVVARFAGGVPVGAVRWPGWAPAALTGLG

Download         Length: 570 bp

>T242623 NZ_OW849064:3238369-3238746 [Escherichia coli]
ATGAACACATTACCCGACACACACGTACGGGAGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAC
CCGACTGCTGGACCAGCACTACGGCCTCACGCTGAATGACACACCGTTCGCCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTGGAAAAATACGCGCTGGTACGAACTGACCAGCCAGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATCAACAGCATTGATATTCTCCGGGCTCGCAGGGCGACCGGCCTGATGACCCGGAA
CAATTACAGAATGGTAAATAACATTACCCAGGGCAAGCATCCGGAGGCAAAACGATGA

Antitoxin


Download         Length: 129 a.a.        Molecular weight: 14024.46 Da        Isoelectric Point: 4.5925

>AT242623 WP_006552789.1 NZ_CP095851:c839960-839574 [Rhodococcus pyridinivorans]
MTSSTDKVTRFDAELVDSAIAEGGRQNRTGRQQLEYWARIGRAMTAHETASLHRVHEALAGTRELSELTAAEGRLFDAEI
DARLADGLARTDYAEILAARGVTTVVLDDEGRLVEQRPDGSRQVLDDA

Download         Length: 387 bp

>AT242623 NZ_OW849064:3237911-3238279 [Escherichia coli]
GTGTCAGACACACTTTCCGGGACAACGCATCCCGATGACAATGACGACCGCCTCTGGTGGGGACTGCCCTGCACCGTGAC
GCCCTGTTTCGGGGCACGTCTGGTGCAGAAGGGTAACCGGTTGCATTACCTTGCCGACCGCGCCGGTATCAGAGGCCGGT
TCAGCGATGCAGATGCATACCACCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGCCATCAGCATACCGTGACACTGTATGCGAAGGGGCTGACCTGTGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCTGAAACGAAAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7T7RLW6

Antitoxin

Source ID Structure
AlphaFold DB H0JT29

References