242536

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2247986..2248131 Replicon chromosome
Accession NZ_CP095776
Organism Klebsiella pneumoniae strain bo714

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2248022..2248124 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2247986..2248131 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MX575_RS10890 (MX575_10890) 2243116..2245176 + 2061 WP_004151449.1 oligopeptidase B -
MX575_RS10895 (MX575_10895) 2245180..2245839 - 660 WP_002911407.1 exodeoxyribonuclease X -
MX575_RS10900 (MX575_10900) 2245918..2246148 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MX575_RS10905 (MX575_10905) 2246261..2246635 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MX575_RS10910 (MX575_10910) 2246639..2247508 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
MX575_RS10915 (MX575_10915) 2247525..2247863 + 339 WP_002911404.1 YebY family protein -
- 2247986..2248131 - 146 - - Antitoxin
- 2248022..2248124 + 103 - - Toxin
MX575_RS10920 (MX575_10920) 2248499..2248642 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MX575_RS10925 (MX575_10925) 2248747..2249715 - 969 WP_004151446.1 VirK/YbjX family protein -
MX575_RS10930 (MX575_10930) 2249872..2250525 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
MX575_RS10935 (MX575_10935) 2250522..2250713 - 192 WP_002911395.1 YebW family protein -
MX575_RS10940 (MX575_10940) 2250811..2251050 - 240 WP_002911393.1 YebV family protein -
MX575_RS10945 (MX575_10945) 2251166..2252599 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T242536 NZ_CP095776:2248022-2248124 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT242536 NZ_CP095776:c2248131-2247986 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References