Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapC-mazE/VapC-MazE
Location 158675..159336 Replicon plasmid pAPA01-011
Accession NC_013210
Organism Acetobacter pasteurianus IFO 3283-01

Toxin (Protein)


Gene name vapC Uniprot ID C7JIL1
Locus tag APA01_RS14420 Protein ID WP_006115553.1
Coordinates 159028..159336 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID C7JIL0
Locus tag APA01_RS14415 Protein ID WP_006115554.1
Coordinates 158675..158929 (-) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
APA01_RS16240 154161..154379 - 219 WP_170315285.1 WGR domain-containing protein -
APA01_RS14370 154458..154736 - 279 WP_006115563.1 HU family DNA-binding protein -
APA01_RS16685 156178..156363 - 186 WP_041633309.1 hypothetical protein -
APA01_RS14390 156448..157263 + 816 WP_012813210.1 hypothetical protein -
APA01_RS14395 157276..157680 + 405 WP_006115557.1 hypothetical protein -
APA01_RS14400 157737..158057 - 321 WP_012813211.1 hypothetical protein -
APA01_RS14405 158087..158287 - 201 WP_012813212.1 hypothetical protein -
APA01_RS14410 158344..158673 - 330 WP_012813213.1 endoribonuclease MazF -
APA01_RS14415 158675..158929 - 255 WP_006115554.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
APA01_RS14420 159028..159336 - 309 WP_006115553.1 PIN domain-containing protein Toxin
APA01_RS14425 159333..159605 - 273 WP_006115552.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
APA01_RS14430 159935..160306 - 372 Protein_155 integrase core domain-containing protein -
APA01_RS14435 160400..161785 + 1386 WP_012813126.1 IS1380-like element IS1380A family transposase -
APA01_RS16255 161917..162368 + 452 Protein_157 recombinase family protein -
APA01_RS14440 162682..163455 - 774 WP_003631418.1 TSUP family transporter -
APA01_RS14445 163647..164231 + 585 Protein_159 IS701 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..191799 191799


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 103 a.a.        Molecular weight: 15177.21 Da        Isoelectric Point: 5.5500

>T24253 WP_006115553.1 NC_013210:c159336-159028 [Acetobacter pasteurianus IFO 3283-01]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 309 bp

>T24253 NC_013210:c159336-159028 [Acetobacter pasteurianus IFO 3283-01]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 12528.03 Da        Isoelectric Point: 5.5500

>AT24253 WP_006115554.1 NC_013210:c158929-158675 [Acetobacter pasteurianus IFO 3283-01]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFF

Download         Length: 255 bp

>AT24253 NC_013210:c158929-158675 [Acetobacter pasteurianus IFO 3283-01]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTT

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A401X8Y0


Antitoxin

Source ID Structure
AlphaFold DB A0A6P1QDC4

References