Detailed information of TA system TA024252

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): mazEF/PRK09907-MazE
• Location: 158344..158929
• Replicon: plasmid pAPA01-011
• Accession: NC_013210
• Organism: Acetobacter pasteurianus IFO 3283-01

Toxin (Protein)

• Gene name: mazF
• Uniprot ID: C7JIK9
• Locus tag: APA01_RS14410
• Protein ID: WP_012813213.1
• Coordinates: 158344..158673 (-)
• Length: 110 a.a.

Antitoxin (Protein)

• Gene name: mazE
• Uniprot ID: C7JIL0
• Locus tag: APA01_RS14415
• Protein ID: WP_006115554.1
• Coordinates: 158675..158929 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
APA01_RS16240	154161..154379	-	219	WP_170315285.1	WGR domain-containing protein	-
APA01_RS14370	154458..154736	-	279	WP_006115563.1	HU family DNA-binding protein	-
APA01_RS16685	156178..156363	-	186	WP_041633309.1	hypothetical protein	-
APA01_RS14390	156448..157263	+	816	WP_012813210.1	hypothetical protein	-
APA01_RS14395	157276..157680	+	405	WP_006115557.1	hypothetical protein	-
APA01_RS14400	157737..158057	-	321	WP_012813211.1	hypothetical protein	-
APA01_RS14405	158087..158287	-	201	WP_012813212.1	hypothetical protein	-
APA01_RS14410	158344..158673	-	330	WP_012813213.1	endoribonuclease MazF	Toxin
APA01_RS14415	158675..158929	-	255	WP_006115554.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
APA01_RS14420	159028..159336	-	309	WP_006115553.1	PIN domain-containing protein	-
APA01_RS14425	159333..159605	-	273	WP_006115552.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-
APA01_RS14430	159935..160306	-	372	Protein_155	integrase core domain-containing protein	-
APA01_RS14435	160400..161785	+	1386	WP_012813126.1	IS1380-like element IS1380A family transposase	-
APA01_RS16255	161917..162368	+	452	Protein_157	recombinase family protein	-
APA01_RS14440	162682..163455	-	774	WP_003631418.1	TSUP family transporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..191799	191799

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 110 a.a.
• Molecular weight: 16207.44 Da
• Isoelectric Point: 5.5500

>T24252 WP_012813213.1 NC_013210:c158673-158344 [Acetobacter pasteurianus IFO 3283-01]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 330 bp

>T24252 NC_013210:c158673-158344 [Acetobacter pasteurianus IFO 3283-01]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTT

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 12528.03 Da
• Isoelectric Point: 5.5500

>AT24252 WP_006115554.1 NC_013210:c158929-158675 [Acetobacter pasteurianus IFO 3283-01]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFF

Nucleotide

• Length: 255 bp

>AT24252 NC_013210:c158929-158675 [Acetobacter pasteurianus IFO 3283-01]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTT

Structures

Toxin

• AlphaFold DB: A0A6P1QFJ7

Antitoxin

• AlphaFold DB: A0A6P1QDC4