Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 3315143..3316865 Replicon chromosome
Accession NZ_CP095765
Organism Proteus mirabilis strain T1010

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag MYO54_RS15435 Protein ID WP_211868028.1
Coordinates 3315143..3316081 (-) Length 313 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag MYO54_RS15440 Protein ID WP_223293371.1
Coordinates 3316074..3316865 (-) Length 264 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MYO54_RS15415 3311084..3311596 - 513 WP_223293369.1 S26 family signal peptidase -
MYO54_RS15420 3311580..3311927 - 348 WP_004249366.1 hypothetical protein -
MYO54_RS15425 3311920..3314319 - 2400 WP_223293370.1 type IV secretion system protein TraC -
MYO54_RS15430 3314319..3315011 - 693 WP_001228924.1 DsbC family protein -
MYO54_RS15435 3315143..3316081 - 939 WP_211868028.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
MYO54_RS15440 3316074..3316865 - 792 WP_223293371.1 type IV toxin-antitoxin system AbiEi family antitoxin Antitoxin
MYO54_RS15445 3317086..3317472 - 387 WP_032469918.1 TraA family conjugative transfer protein -
MYO54_RS15450 3317469..3318041 - 573 WP_148039504.1 type IV conjugative transfer system lipoprotein TraV -
MYO54_RS15455 3318116..3319405 - 1290 WP_159262611.1 TraB/VirB10 family protein -
MYO54_RS15460 3319408..3320304 - 897 WP_159262630.1 type-F conjugative transfer system secretin TraK -
MYO54_RS15465 3320288..3320914 - 627 WP_159262613.1 TraE/TraK family type IV conjugative transfer system protein -
MYO54_RS15470 3320911..3321192 - 282 WP_000433891.1 type IV conjugative transfer system protein TraL -
MYO54_RS15475 3321373..3321696 + 324 WP_001896384.1 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element tet(J) / sul2 / aph(3'')-Ib / aph(6)-Id / aph(3')-VIa - 3221237..3347821 126584


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(14-278)

Antitoxin

Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system

(99-250)


Sequences

Toxin        


Download         Length: 313 a.a.        Molecular weight: 35578.85 Da        Isoelectric Point: 4.9081

>T242504 WP_211868028.1 NZ_CP095765:c3316081-3315143 [Proteus mirabilis]
MDKDSPYYKQVSLLIRMLPVVATETVFALKGGTAINLFVRDFPRLSVDIDLAYLPLEPRDEALINVRAALQRITDRINTQ
PDIRAAFQDNKADELRIVVSSPVATIKIEVSPVARGTLHSAEIMPVQESVEDEFGYAEIQVVSLPDLYGGKLCAAMDRQH
PRDLFDVRMLLGSEGISREILVGFLTYTLSHPRPINEVMSPNWQPLNEKFQAEFDGMTFEKVECEDLASVRPMMLIELQK
HFTERDHAFLMSFKRGQPDWALFDYPNAADLPAIRWKLQNINKLAKNQTKHQEQLDKLKQVLDDWLVNANAE

Download         Length: 939 bp

>T242504 NZ_OW704627:1820134-1820622 [Salmonella enterica subsp. enterica serovar Typhi]
ATGATCTCCGCCCCTGAACCGCTTCATGCCGGGCATATTCTTACCCCCTTCTGCTGCGGTGTGGATTCAATGGATAACTG
GCTAAAACAGCGGGCGATGAAAAATCAGGTAACTGGCGCATCCCGTACCTTTGTGTGTTGCGGCAGCGATTCTGACGTAC
TGGCGTATTATTCGCTGGCGTCCAGCGCGGTAACGACAAACACCGCCCCCGGTCGCTTTCGTCGCAATATGCCCGATCCG
ATCCCGGTTGTGGTGCTGGGCCGTCTGGCGGTGGATCGGTCGCTACATGGGCAGGGCGTAGGTCGGGCGCTGGTGAGGGA
TGCCGGGCTGCGGGTGATTCAGGTGGCGGAAACTATCGGTATTCGCGGGATGCTGGTCCATGCCCTGTCGGATGAAGCGC
GGGAGTTTTACCTGCGGGTGGGGTTTGAGCCGTCGCCGATGGATCCGATGATGTTGATGGTGACGTTGGGGGATTTGGTT
CATGCCTGA

Antitoxin


Download         Length: 264 a.a.        Molecular weight: 30195.54 Da        Isoelectric Point: 9.3573

>AT242504 WP_223293371.1 NZ_CP095765:c3316865-3316074 [Proteus mirabilis]
MSSKINWLVAHTSPGALVLQQWLTENGVSYSLAQKYTQNGWLKKLSSGVYYRPNAQGDIKPTWVDAIQALDVQLGVPVHL
AGLSSLTHQGLSHYLQLNKEQVWICVKNKSSLPKWFREFPYQNWFYCGNHKLEVNPEKDLKRIRVKEKELTVSCAELAAY
EVVDAIGKLISFEHVAELFQGLVNLSPRKVQDILERSSSVQANRIFLFLGRYYDHQWVNRIDETRIELGAGKRQVVEKGR
FDERYQITVPEILSVKKGEQHNG

Download         Length: 792 bp

>AT242504 NZ_OW704627:1819844-1820137 [Salmonella enterica subsp. enterica serovar Typhi]
ATGCCAGTCGCAAACAGTATGGCGATGAAACGCGAAACCCTGAACCTGCGCATCAAGCCCGCCGAGCGCGATCTTATCGA
TCGGGCTGCAAAAGCCAGAGGGAAAAACTGCACAGACTTTGTGCTAGAAGCTGCCCGCGCCGCCGCCGAGGAAGCGCTGA
TCGAGCAACGCATCATTATGGCCGATCCAGAGGCTTATCAGGCATTTCTGATCCGTCTGGATCAGGCTCCTGCGCCAAAC
GATGCGTTGCGTAAAACCATGCAGACTCCTGCACCGTGGGAGCAGGAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References