Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2200709..2200877 Replicon chromosome
Accession NZ_CP095761
Organism Klebsiella michiganensis strain K254

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2200767..2200870 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2200709..2200877 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MMY93_RS10550 (MMY93_10550) 2195836..2197896 + 2061 WP_197664200.1 oligopeptidase B -
MMY93_RS10555 (MMY93_10555) 2197903..2198562 - 660 WP_004852093.1 exodeoxyribonuclease X -
MMY93_RS10560 (MMY93_10560) 2198641..2198871 - 231 WP_004103351.1 DNA polymerase III subunit theta -
MMY93_RS10565 (MMY93_10565) 2199007..2199381 + 375 WP_004852090.1 CopC domain-containing protein YobA -
MMY93_RS10570 (MMY93_10570) 2199386..2200255 + 870 WP_004852088.1 copper homeostasis membrane protein CopD -
MMY93_RS10575 (MMY93_10575) 2200272..2200610 + 339 WP_004103344.1 YebY family protein -
- 2200709..2200877 - 169 - - Antitoxin
- 2200767..2200870 + 104 - - Toxin
MMY93_RS10580 (MMY93_10580) 2200995..2201954 - 960 WP_109212701.1 spore coat protein U domain-containing protein -
MMY93_RS10585 (MMY93_10585) 2201969..2204299 - 2331 WP_004852083.1 fimbria/pilus outer membrane usher protein -
MMY93_RS10590 (MMY93_10590) 2204302..2205066 - 765 WP_004852081.1 fimbria/pilus periplasmic chaperone -
MMY93_RS10595 (MMY93_10595) 2205085..2205603 - 519 WP_004852079.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T242467 NZ_CP095761:2200767-2200870 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT242467 NZ_CP095761:c2200877-2200709 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References