Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | hicAB/- |
| Location | 2120856..2121445 | Replicon | chromosome |
| Accession | NZ_CP095742 | ||
| Organism | Luteibacter aegosomatissinici strain 353 | ||
Toxin (Protein)
| Gene name | hicA | Uniprot ID | - |
| Locus tag | L2Y97_RS09515 | Protein ID | WP_247435941.1 |
| Coordinates | 2121191..2121445 (-) | Length | 85 a.a. |
Antitoxin (Protein)
| Gene name | hicB | Uniprot ID | - |
| Locus tag | L2Y97_RS09510 | Protein ID | WP_247435938.1 |
| Coordinates | 2120856..2121194 (-) | Length | 113 a.a. |
Genomic Context
Location: 2118448..2120403 (1956 bp)
Type: Others
Protein ID: WP_247435934.1
Type: Others
Protein ID: WP_247435934.1
Location: 2120508..2120852 (345 bp)
Type: Others
Protein ID: WP_247435936.1
Type: Others
Protein ID: WP_247435936.1
Location: 2121593..2122189 (597 bp)
Type: Others
Protein ID: WP_247435944.1
Type: Others
Protein ID: WP_247435944.1
Location: 2122323..2123036 (714 bp)
Type: Others
Protein ID: WP_247435947.1
Type: Others
Protein ID: WP_247435947.1
Location: 2124657..2124968 (312 bp)
Type: Others
Protein ID: WP_247435952.1
Type: Others
Protein ID: WP_247435952.1
Location: 2124965..2125366 (402 bp)
Type: Others
Protein ID: WP_247435955.1
Type: Others
Protein ID: WP_247435955.1
Location: 2116289..2116927 (639 bp)
Type: Others
Protein ID: WP_247435928.1
Type: Others
Protein ID: WP_247435928.1
Location: 2117220..2118341 (1122 bp)
Type: Others
Protein ID: WP_247435931.1
Type: Others
Protein ID: WP_247435931.1
Location: 2120856..2121194 (339 bp)
Type: Antitoxin
Protein ID: WP_247435938.1
Type: Antitoxin
Protein ID: WP_247435938.1
Location: 2121191..2121445 (255 bp)
Type: Toxin
Protein ID: WP_247435941.1
Type: Toxin
Protein ID: WP_247435941.1
Location: 2123046..2124329 (1284 bp)
Type: Others
Protein ID: WP_247435949.1
Type: Others
Protein ID: WP_247435949.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L2Y97_RS09485 (L2Y97_09485) | 2116289..2116927 | - | 639 | WP_247435928.1 | MarC family protein | - |
| L2Y97_RS09495 (L2Y97_09495) | 2117220..2118341 | - | 1122 | WP_247435931.1 | ribonuclease D | - |
| L2Y97_RS09500 (L2Y97_09500) | 2118448..2120403 | + | 1956 | WP_247435934.1 | formylglycine-generating enzyme family protein | - |
| L2Y97_RS09505 (L2Y97_09505) | 2120508..2120852 | + | 345 | WP_247435936.1 | hypothetical protein | - |
| L2Y97_RS09510 (L2Y97_09510) | 2120856..2121194 | - | 339 | WP_247435938.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
| L2Y97_RS09515 (L2Y97_09515) | 2121191..2121445 | - | 255 | WP_247435941.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
| L2Y97_RS09520 (L2Y97_09520) | 2121593..2122189 | + | 597 | WP_247435944.1 | TetR/AcrR family transcriptional regulator | - |
| L2Y97_RS09525 (L2Y97_09525) | 2122323..2123036 | + | 714 | WP_247435947.1 | SDR family oxidoreductase | - |
| L2Y97_RS09530 (L2Y97_09530) | 2123046..2124329 | - | 1284 | WP_247435949.1 | PAS domain-containing methyl-accepting chemotaxis protein | - |
| L2Y97_RS09535 (L2Y97_09535) | 2124657..2124968 | + | 312 | WP_247435952.1 | hypothetical protein | - |
| L2Y97_RS09540 (L2Y97_09540) | 2124965..2125366 | + | 402 | WP_247435955.1 | Rap1a/Tai family immunity protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 85 a.a. Molecular weight: 9412.84 Da Isoelectric Point: 11.3689
>T242458 WP_247435941.1 NZ_CP095742:c2121445-2121191 [Luteibacter aegosomatissinici]
MTSRHQRTLDLIATRPTSGNVKWADIVALLRHLGASLREAEGSRITVLLFGEVRVFHRPHPSPDTDKGAVADIRKWLYRN
GVIA
MTSRHQRTLDLIATRPTSGNVKWADIVALLRHLGASLREAEGSRITVLLFGEVRVFHRPHPSPDTDKGAVADIRKWLYRN
GVIA
Download Length: 255 bp
>T242458 NZ_OW443151:c344754-344476 [Vibrio cholerae]
ATGATTTTCTGGGAAGAAGCATCTCTCAATGATCGTGAGAAAATTTTCGAATTTCTTTACGACTTTAACCCAGCAGCCGC
AGAAAAAACGGATGAGCTCATAGAAACCAAAGTCGAAAATTTGCTTGAGCAACCACTAATGGGGGTTCAGCGTGATGGTA
TTCGAGGCAGATTGCTTATTATCCCTGAGATATCAATGATTGTTTCGTATTGGGTTGATGGTTCTAAAATTCGAATAATG
CGTGTACTACATCAGAAACAAAAATTTCCAAACGACTGA
ATGATTTTCTGGGAAGAAGCATCTCTCAATGATCGTGAGAAAATTTTCGAATTTCTTTACGACTTTAACCCAGCAGCCGC
AGAAAAAACGGATGAGCTCATAGAAACCAAAGTCGAAAATTTGCTTGAGCAACCACTAATGGGGGTTCAGCGTGATGGTA
TTCGAGGCAGATTGCTTATTATCCCTGAGATATCAATGATTGTTTCGTATTGGGTTGATGGTTCTAAAATTCGAATAATG
CGTGTACTACATCAGAAACAAAAATTTCCAAACGACTGA
Antitoxin
Download Length: 113 a.a. Molecular weight: 12438.25 Da Isoelectric Point: 5.6398
>AT242458 WP_247435938.1 NZ_CP095742:c2121194-2120856 [Luteibacter aegosomatissinici]
MNNIMVIDGHRAVVQYDPEIDMFRGEFVGLNGGADFYAPDVEGLRREGVISLRVFMEACREAGIPAVRTFSGKFQARVTA
ELHLRSTEAAAARGISLNQFVQHAMERELLVV
MNNIMVIDGHRAVVQYDPEIDMFRGEFVGLNGGADFYAPDVEGLRREGVISLRVFMEACREAGIPAVRTFSGKFQARVTA
ELHLRSTEAAAARGISLNQFVQHAMERELLVV
Download Length: 339 bp
>AT242458 NZ_OW443151:c345035-344751 [Vibrio cholerae]
ATGGATACTAGAATTCAATTTCGTGTAGACGAAGAAACAAAACGTTTAGCTCAACAAATGGCTGAAAGCCAAGGTCGGAC
TCTTAGCGATGCTTGCCGTGAACTCACCGAACAATTAGCTGAACAGCAACGCAAGGCATTATCTCACGATGCATGGCTAA
CTGAACAAGTGAATCAAGCATTTGAGAAGTTCGACTCAGGAAAAGCGGTATTCGTTGAACATGACATCGCCAAAGTGCGA
ATGGCTGAACGTAAAGCTAAAATCCGAAATCGAGGTCACGCATGA
ATGGATACTAGAATTCAATTTCGTGTAGACGAAGAAACAAAACGTTTAGCTCAACAAATGGCTGAAAGCCAAGGTCGGAC
TCTTAGCGATGCTTGCCGTGAACTCACCGAACAATTAGCTGAACAGCAACGCAAGGCATTATCTCACGATGCATGGCTAA
CTGAACAAGTGAATCAAGCATTTGAGAAGTTCGACTCAGGAAAAGCGGTATTCGTTGAACATGACATCGCCAAAGTGCGA
ATGGCTGAACGTAAAGCTAAAATCCGAAATCGAGGTCACGCATGA