Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 2575350..2575886 Replicon chromosome
Accession NZ_CP095741
Organism Luteibacter aegosomaticola strain 335

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag L2Y96_RS11255 Protein ID WP_247325582.1
Coordinates 2575350..2575613 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L2Y96_RS11260 Protein ID WP_247325583.1
Coordinates 2575620..2575886 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2Y96_RS11230 (L2Y96_11230) 2570629..2571351 - 723 WP_247325577.1 murein L,D-transpeptidase catalytic domain family protein -
L2Y96_RS11235 (L2Y96_11235) 2571490..2573226 + 1737 WP_247325578.1 L,D-transpeptidase family protein -
L2Y96_RS11240 (L2Y96_11240) 2573287..2574018 + 732 WP_247325579.1 2OG-Fe dioxygenase family protein -
L2Y96_RS11245 (L2Y96_11245) 2574123..2574443 + 321 WP_247325580.1 2-hydroxyacyl-CoA dehydratase -
L2Y96_RS11250 (L2Y96_11250) 2574462..2575340 + 879 WP_247325581.1 bestrophin family protein -
L2Y96_RS11255 (L2Y96_11255) 2575350..2575613 - 264 WP_247325582.1 Txe/YoeB family addiction module toxin Toxin
L2Y96_RS11260 (L2Y96_11260) 2575620..2575886 - 267 WP_247325583.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
L2Y96_RS11265 (L2Y96_11265) 2576004..2576432 + 429 WP_247325585.1 MarR family transcriptional regulator -
L2Y96_RS11270 (L2Y96_11270) 2576429..2578183 + 1755 WP_247325587.1 chloride channel protein -
L2Y96_RS11275 (L2Y96_11275) 2578180..2579766 - 1587 WP_247325590.1 inorganic phosphate transporter -
L2Y96_RS11280 (L2Y96_11280) 2579870..2580685 + 816 WP_247325592.1 CHAD domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10156.77 Da        Isoelectric Point: 9.7810

>T242454 WP_247325582.1 NZ_CP095741:c2575613-2575350 [Luteibacter aegosomaticola]
MARKLTFTSKGWADYASWADDRKMLARVNLLIRECLRTPTEGLAKPKPMRGDLAGAWSRRIDERHRLVYLFTDHELEVIA
CRLHTTE

Download         Length: 264 bp

>T242454 NZ_OW443151:c332481-332164 [Vibrio cholerae]
ATGCAAAATAAACAATATAAGCTCAGCCAATTAGCCCAAGAGCACTTACTCAAGATTAAACACTACACCATTGAAAATTT
CGCTGAAGCGCAGTGGCAAAAATATAAGCCGACCTTGCTTTCAGGTTTCCAAACTCTAGCGGATAACCCAGGACTAGGAA
AAAGCTGTGAAGATATTTACCAAAATGGTTTTTACTTTCCAGTTGGAAAACACATGGCTTATTACACCAAAGAAGCAAAC
TTCATTCTCATAGTCGCAGTATTAGGGCAATCACAACTACCCCAAAAACATCTCAAACAGTCACGCTTTGTTTCTTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9833.00 Da        Isoelectric Point: 4.3885

>AT242454 WP_247325583.1 NZ_CP095741:c2575886-2575620 [Luteibacter aegosomaticola]
MRAINYSEVRNNLATVLDTVVDDAEVAVITRRGDADGSRAVYLVPARLWESMEETAYLLSGANRGHILESLRQARAGEVF
ERPLIEDE

Download         Length: 267 bp

>AT242454 NZ_OW443151:c332742-332500 [Vibrio cholerae]
ATGCACACACTAACAGCAAATGATGCTAAACGAAATTTTGGTGAACTTCTTCTAAGCGCACAGCGCGAACCTGTCATCAT
CAGCAAAAACAGTAAGAATACTGTCGTTGTCATGTCCATTAAGGATTTTGAAGAGCTTGAAGCCATGAAACTCGATTATC
TCAAACACTGCTTTGAGTCTGCTCAGAAAGACTTAGATAGTGGCAAAACCGTTGATGGTGCCGCTTTTCTAAACACCCTT
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References