Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 820366..821000 Replicon chromosome
Accession NZ_CP095741
Organism Luteibacter aegosomaticola strain 335

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag L2Y96_RS03615 Protein ID WP_247332369.1
Coordinates 820366..820770 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag L2Y96_RS03620 Protein ID WP_247332372.1
Coordinates 820770..821000 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2Y96_RS03595 (L2Y96_03595) 817267..818025 - 759 WP_247332359.1 aspartyl/asparaginyl beta-hydroxylase domain-containing protein -
L2Y96_RS03600 (L2Y96_03600) 818049..818783 - 735 WP_247332362.1 hypothetical protein -
L2Y96_RS03605 (L2Y96_03605) 818780..819496 - 717 WP_247332364.1 hypothetical protein -
L2Y96_RS03610 (L2Y96_03610) 819645..820376 + 732 WP_247332366.1 thymidylate kinase -
L2Y96_RS03615 (L2Y96_03615) 820366..820770 - 405 WP_247332369.1 PIN domain-containing protein Toxin
L2Y96_RS03620 (L2Y96_03620) 820770..821000 - 231 WP_247332372.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
L2Y96_RS03625 (L2Y96_03625) 821065..823890 - 2826 WP_247332374.1 type 2 lanthipeptide synthetase LanM family protein -
L2Y96_RS03630 (L2Y96_03630) 823966..824154 - 189 WP_247332377.1 DUF6229 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-113)

Antitoxin

SpoVT-AbrB domain

(5-36)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14714.90 Da        Isoelectric Point: 6.3716

>T242451 WP_247332369.1 NZ_CP095741:c820770-820366 [Luteibacter aegosomaticola]
MEGLTFLDSNVVLYLLSEDTEKHDIAMDLLSRRPAVSVQVLNEVTNVCRKKAGMSWEEVAAFLASIRHFCPVVSLTADIH
DSARRLAARHKLSFYDANIVAAAIDSGAAVVWSEAMHHGLVIEHTVTVVNPFKG

Download         Length: 405 bp

>T242451 NZ_OW443151:321609-321896 [Vibrio cholerae]
ATGAAAGTAGTTTGGTCACCTCTAGCGTTACAAAAACTGGGTGATGCCGCAGAGTTTATTGCTTTGGATAACCCATCAGC
TGCAGAAAAGTGGGTGAATGAAGTATTCGACAAAACGGAATTGCTCGGCTCAATGCCAGAAATGGGCCGCATGGTTCCTG
AAATGCCTCATACGAACTACCGTGAAATAATTTTTGGTCATTACCGCATTATTTATAGTTTGAGCCACGAAATCCGCGTT
CTAACAGTTCGTAACTGTCGTCAATTGCTCACGGAACATGATGTGTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8595.75 Da        Isoelectric Point: 6.3659

>AT242451 WP_247332372.1 NZ_CP095741:c821000-820770 [Luteibacter aegosomaticola]
MRVSKWGNSLGIRLPAAVVEALGLREGDDVVLYAKGAREFAVERGPRDEEVLERLRALKGRLPADFRFDRDDANER

Download         Length: 231 bp

>AT242451 NZ_OW443151:321331-321612 [Vibrio cholerae]
ATGAGCCGTATTCACCTTGATCAAGATATTCAGCCTTTGTCTGAGTTCCGTGCTGGCGTTGCATCATTTATCAAACAGAT
CAATGAGACTCGTCGACCATTGGTTATTACACAACGAGGTAAAGGTGTAGCCGTTGTTCTTGACGTTGCGGAGTATGAAG
CAATGCAAGAGAAAATCGAATTACTCGAAGAAATGCGTACTGCAGAAGCTCAATTGGCTGCAGGTTTAGGTATATCAAAC
GAAGATGCTCGTTCACAAGTTCTGGGGCGTATCATCAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References