Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 768315..769788 Replicon chromosome
Accession NZ_CP095741
Organism Luteibacter aegosomaticola strain 335

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag L2Y96_RS03425 Protein ID WP_247332223.1
Coordinates 768937..769788 (+) Length 284 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag L2Y96_RS03420 Protein ID WP_247332221.1
Coordinates 768315..768923 (+) Length 203 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2Y96_RS03400 (L2Y96_03400) 763560..765728 - 2169 WP_247332213.1 TonB-dependent siderophore receptor -
L2Y96_RS03405 (L2Y96_03405) 766064..766720 + 657 WP_247332215.1 hypothetical protein -
L2Y96_RS03410 (L2Y96_03410) 766729..767310 - 582 WP_247332217.1 hypothetical protein -
L2Y96_RS03415 (L2Y96_03415) 767524..768069 - 546 WP_247332219.1 DUF922 domain-containing protein -
L2Y96_RS03420 (L2Y96_03420) 768315..768923 + 609 WP_247332221.1 AbiEi antitoxin N-terminal domain-containing protein Antitoxin
L2Y96_RS03425 (L2Y96_03425) 768937..769788 + 852 WP_247332223.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
L2Y96_RS03430 (L2Y96_03430) 769898..770356 + 459 WP_247332232.1 YccF domain-containing protein -
L2Y96_RS03435 (L2Y96_03435) 770905..772317 + 1413 WP_247332234.1 hypothetical protein -
L2Y96_RS03440 (L2Y96_03440) 772453..773745 + 1293 WP_247332236.1 DUF4189 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(34-262)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(8-53)


Sequences

Toxin        


Download         Length: 284 a.a.        Molecular weight: 31511.29 Da        Isoelectric Point: 6.2452

>T242450 WP_247332223.1 NZ_CP095741:768937-769788 [Luteibacter aegosomaticola]
MMDLAVSIAHRLRNHAAENQQDFNAVLTRFASERLLFRLSQSEHAKSFLLKGALLFLLWHDLPERPTRDIDLLGFGEEDV
ESIESIFREVCAIDASDAVVFEPASVRGATIRKQAGYGGVRITLLGKLKNVRLHVQVDVGFGDAVTPAASEEVFPVVLAD
LPAPILRVYPKYTVCAEKLEAISALGMANTRLKDFYDMWLLLTPRDMDDDMLGSAIAATFNRRKRPIGDEWPVGLTDEFA
ADSQRQRQWQAFLAKNGLVAPPLSDVLATLRHCLSVPLDKARK

Download         Length: 852 bp

>T242450 NZ_OW443151:320515-320802 [Vibrio cholerae]
ATGACATTAGAATTTAAAGATAAGTGGTTAGAGCAGTTTTACGAGGATGATAAACGACATCGTTTAATTCCAGGTAGCAT
AGAGAATGCTCTATTTCGGAAGCTGGAAATCTTAGATGCAGCTCAAGCTGAATCAGACTTAAGAATTCCACCGGGTAATC
GTTTTGAACATCTTGAAGGAAATCTTAAAGGTTGGTGTTCAATTCGAGTGAACAAACAGTATCGTTTGATTTTTCAGTGG
GTTGATGGTGTTGCACTAAATACTTACTTAGACCCACATAAGTATTGA

Antitoxin


Download         Length: 203 a.a.        Molecular weight: 22244.99 Da        Isoelectric Point: 10.1908

>AT242450 WP_247332221.1 NZ_CP095741:768315-768923 [Luteibacter aegosomaticola]
MPRKIAEDQILALARDVGVIRARDIAARGIPTVVLSRMVAAGQLERVSRGLYTHPGTSPSEHRSLAEVAARIPSGVVCLL
TALRYYGIGTQSPLAVWVAIPSQAPTPRLAHVRIRYVWMTPSPLTEGVTEVNIEGVSVKVFSIAKTIADCFKFRNKIGLD
VAVEALADAWRRDLVSMDDLWRFAKIDRVANVMRPYLESLTV

Download         Length: 609 bp

>AT242450 NZ_OW443151:320813-321130 [Vibrio cholerae]
ATGCGTAAGACAAAACGTCGTCCAGTTAGCGTTGGGCAAATGTTAAAAGTTGAATTTCTTGAACCAATGGGCATCACATC
AAAAGCGCTCGCTGAAGCGATGGGTGTACACAGAAATACGGTGAGTAATTTGATTAATGGCGGAGTGTTAACAGCTCCGG
TAGCAATCAAGTTAGCCGCGGCATTAGGTAATACACCAGAATTTTGGCTTAACATTCAACATGCAGTTGATCTTTGGGAT
ACGAGAAATCGTTATCAAGAAGAAGTAAAGTTTGTAAAGCCGTTGTTTGTTTCGCTGGAACAAAGCGCACGTACATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References