Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 25669..26162 Replicon plasmid unnamed
Accession NZ_CP095729
Organism Listeria innocua strain 2015L-6726

Toxin (Protein)


Gene name relE Uniprot ID A0A686CL10
Locus tag AS079_RS14590 Protein ID WP_031642448.1
Coordinates 25669..25944 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A459UCT8
Locus tag AS079_RS14595 Protein ID WP_031642450.1
Coordinates 25941..26162 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AS079_RS14570 (AS079_14570) 20739..22685 - 1947 WP_049961603.1 hypothetical protein -
AS079_RS14575 (AS079_14575) 22682..23221 - 540 WP_049961604.1 hypothetical protein -
AS079_RS14580 (AS079_14580) 23223..23495 - 273 WP_031642446.1 DUF5592 family protein -
AS079_RS14585 (AS079_14585) 23512..25431 - 1920 WP_031642447.1 hypothetical protein -
AS079_RS14590 (AS079_14590) 25669..25944 - 276 WP_031642448.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AS079_RS14595 (AS079_14595) 25941..26162 - 222 WP_031642450.1 DUF6290 family protein Antitoxin
AS079_RS14600 (AS079_14600) 26245..28569 - 2325 WP_049961605.1 type IV secretory system conjugative DNA transfer family protein -
AS079_RS14605 (AS079_14605) 28573..29124 - 552 WP_031642452.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..69303 69303


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-89)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10899.55 Da        Isoelectric Point: 10.2899

>T242434 WP_031642448.1 NZ_CP095729:c25944-25669 [Listeria innocua]
MSKHFHVRFEKEAQKVLKKMDRFQAKLILSWIEKHIEGTDDPRQHGKSLVGNRSGQWRYRVGDYRLIAEIQDNEVIVLIL
NIGHRRDIYDK

Download         Length: 276 bp

>T242434 NZ_OW443148:c388693-388415 [Vibrio cholerae]
ATGATTTTCTGGGAAGAAGCATCTCTCAATGATCGTGAGAAAATTTTCGAATTTCTCTACGACTTTAACCCAGCAGCGGC
TAAAAAAACGGATGAGCTCATAGAAGCCAAAGTCGAAAATTTGCTTGAGCAACCACTAATCGGTGTTCAGCGTGATGGCA
TTAGAGGCAGATTGCTTATTATCCCTGAGATATCAATGATTGTTTCGTATTGGGTTGATGGTTCTAAAATTCGAATAATG
CGTGTACTACATCAGAAACAAAAATTTCCAAACGACTGA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8475.73 Da        Isoelectric Point: 4.8605

>AT242434 WP_031642450.1 NZ_CP095729:c26162-25941 [Listeria innocua]
MTTITFRVSDKEKAFIQEMAKLNGISISELSRKKIIEGLEDQIDLQSYERAIKAHQVKDESISFDEMKKELEL

Download         Length: 222 bp

>AT242434 NZ_OW443148:c388974-388690 [Vibrio cholerae]
ATGGATACTAGAATTCAATTTCGTGTAGACGAAGAAACAAAACGTTTAGCTCAACAAATGGCTGAAAGCCAAGGTCGAAC
TCTTAGCGATGCTTGCCGTGAACTCACTGAACAATTAGCTGAGCAGCAACGCAAGGCATTATCTCACGATGCATGGCTAA
CTGAACAAGTGAATCAAGCATTTGAGAAGTTCGACTCAGGAAAAGCAGTATTCATTGAACATGACATCGCCAAAGCACGA
ATGGCTGAACGTAAAGCTAAAATCCGAAATCGAGGCCACGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A686CL10

Antitoxin

Source ID Structure
AlphaFold DB A0A459UCT8

References