Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 25791..26284 Replicon plasmid unnamed
Accession NZ_CP095722
Organism Listeria innocua strain 2015L-6714

Toxin (Protein)


Gene name relE Uniprot ID A0A686CL10
Locus tag QMZ19_RS00150 Protein ID WP_031642448.1
Coordinates 25791..26066 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A459UCT8
Locus tag QMZ19_RS00155 Protein ID WP_031642450.1
Coordinates 26063..26284 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMZ19_RS00130 (MXK34_00130) 20861..22807 - 1947 WP_049961603.1 hypothetical protein -
QMZ19_RS00135 (MXK34_00135) 22804..23343 - 540 WP_049961604.1 hypothetical protein -
QMZ19_RS00140 (MXK34_00140) 23345..23617 - 273 WP_031642446.1 DUF5592 family protein -
QMZ19_RS00145 (MXK34_00145) 23634..25553 - 1920 WP_031642447.1 hypothetical protein -
QMZ19_RS00150 (MXK34_00150) 25791..26066 - 276 WP_031642448.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QMZ19_RS00155 (MXK34_00155) 26063..26284 - 222 WP_031642450.1 DUF6290 family protein Antitoxin
QMZ19_RS00160 (MXK34_00160) 26367..28691 - 2325 WP_049961605.1 type IV secretory system conjugative DNA transfer family protein -
QMZ19_RS00165 (MXK34_00165) 28695..29246 - 552 WP_031642452.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..69229 69229


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-89)

Antitoxin

Protein of unknown function DUF6290

(1-71)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10899.55 Da        Isoelectric Point: 10.2899

>T242428 WP_031642448.1 NZ_CP095722:c26066-25791 [Listeria innocua]
MSKHFHVRFEKEAQKVLKKMDRFQAKLILSWIEKHIEGTDDPRQHGKSLVGNRSGQWRYRVGDYRLIAEIQDNEVIVLIL
NIGHRRDIYDK

Download         Length: 276 bp

>T242428 NZ_OW370493:c647564-647283 [Rickettsia endosymbiont of Oedothorax gibbosus]
ATGCGAACGATTAAGCGTACTACACAATTTAAACGTGATTATACAAGAGAAAAACGTAGACAACATGGCGTAACTTTGGA
TAATGATTTATCGAAAGCGATTGAATTGTTAGTCATTGATGCACAATTACCTAAATGCATGCGTGAGCATCCTCTCATCG
GTGATTGGAAAGATTGCCGAGATTGTCATATTAAATCCGATCTTGTGCTTATCTATCAGAAGTCGGATGATTACACGCTG
AAATTAATTCGCCTTGGTTCACACAGTGAACTTAGTTTATAA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8475.73 Da        Isoelectric Point: 4.8605

>AT242428 WP_031642450.1 NZ_CP095722:c26284-26063 [Listeria innocua]
MTTITFRVSDKEKAFIQEMAKLNGISISELSRKKIIEGLEDQIDLQSYERAIKAHQVKDESISFDEMKKELEL

Download         Length: 222 bp

>AT242428 NZ_OW370493:c647814-647551 [Rickettsia endosymbiont of Oedothorax gibbosus]
ATGGCTGTTAATACTACTGTTCGTGCTCGCATTGATGAGAATATAAAAGAGGAAGCTTCTATTGTACTATCAACTATGGG
GCTTACTGTATCAGATGCTTTTCGTATGCTTCTAACCCGTATTGCACGCGAAAAAGCCTTGCCTTTTGATCCACTTGTAC
CAAATGCTAAAACAATTGAGGCTATAAAAGCCGCACGAAGTGGTAAACTAATAACTATTGGTAGCATAAATAATTTATTA
ACTGATTTAAATGCGAACGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A686CL10

Antitoxin

Source ID Structure
AlphaFold DB A0A459UCT8

References