Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1828363..1828634 Replicon chromosome
Accession NZ_CP095538
Organism Escherichia coli strain GN04592

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1828493..1828596 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1828363..1828634 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MW396_RS08670 1824918..1825580 - 663 WP_000944256.1 exodeoxyribonuclease X -
MW396_RS08675 1825604..1826260 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
MW396_RS08680 1826362..1826592 - 231 WP_000916763.1 DNA polymerase III subunit theta -
MW396_RS08685 1826731..1827105 + 375 WP_000204705.1 CopC domain-containing protein YobA -
MW396_RS08690 1827109..1827981 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
MW396_RS08695 1827994..1828335 + 342 WP_000976481.1 YebY family protein -
- 1828363..1828634 - 272 - - Antitoxin
- 1828493..1828596 + 104 - - Toxin
MW396_RS08700 1828731..1829387 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
MW396_RS08705 1829388..1829579 - 192 WP_001296140.1 YebW family protein -
MW396_RS08710 1829684..1829920 - 237 WP_001295499.1 YebV family protein -
MW396_RS08715 1830038..1831477 - 1440 WP_001309555.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1821053..1844473 23420


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T242355 NZ_CP095538:1828493-1828596 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT242355 NZ_CP095538:c1828634-1828363 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References