Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3101501..3101772 Replicon chromosome
Accession NZ_CP095533
Organism Escherichia coli strain GN02461

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3101539..3101642 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3101501..3101772 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MW400_RS14510 3098658..3100097 + 1440 WP_024176277.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
MW400_RS14515 3100215..3100451 + 237 WP_001295499.1 YebV family protein -
MW400_RS14520 3100556..3100747 + 192 WP_001296140.1 YebW family protein -
MW400_RS14525 3100748..3101404 - 657 WP_000812713.1 protein-serine/threonine phosphatase -
- 3101501..3101772 + 272 - - Antitoxin
- 3101539..3101642 - 104 - - Toxin
MW400_RS14530 3101800..3102141 - 342 WP_000976490.1 YebY family protein -
MW400_RS14535 3102154..3103026 - 873 WP_000879329.1 copper homeostasis membrane protein CopD -
MW400_RS14540 3103030..3103404 - 375 WP_000168747.1 CopC domain-containing protein YobA -
MW400_RS14545 3103543..3103773 + 231 WP_000916763.1 DNA polymerase III subunit theta -
MW400_RS14550 3103875..3104531 + 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
MW400_RS14555 3104555..3105217 + 663 WP_000944239.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3085661..3109082 23421


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T242333 NZ_CP095533:c3101642-3101539 [Escherichia coli]
GGCAAGGCATCTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT242333 NZ_CP095533:3101501-3101772 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGATGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References